Integration of Trypanosoma cruzi kDNA minicircle sequence in the host genome may be associated with autoimmune serum factors in Chagas disease patients

Integration of kDNA sequences within the genome of the host cell shown by PCR amplification with primers to the conserved Trypanosoma cruzi kDNA minicircle sequence was confirmed by Southern hybridization with specific probes. The cells containing the integrated kDNA sequences were then perpetuated...

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Bibliographic Details
Published in:	Memorias do Instituto Oswaldo Cruz
Main Authors:	Augusto Simões-Barbosa, Ana Maria Barros, Nadjar Nitz, Enrique R Argañaraz, Antonio RL Teixeira
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 1999-09-01
Subjects:	horizontal gene transfer Trypanosoma cruzi kDNA Chagas disease autoimmunity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700041

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