METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE: UPDATE

ABSTRACT Background: Since Ludwig proposed the term “nonalcoholic steatohepatitis” (NASH) for this liver disease in 1980, there have been many advances in understanding it, including its epidemiology, pathogenesis, diagnostic methods, and treatment. Objective: This literature review aims to discus...

Full description

Bibliographic Details
Published in:	Arquivos de Gastroenterologia
Main Authors:	Maria Gabriela Fernandes DEZAN, Claudia Pinto OLIVEIRA, Helma Pinchemel COTRIM
Format:	Article
Language:	English
Published:	Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2025-09-01
Subjects:	Steatotic liver disease metabolic dysfunction-associated steatotic liver disease MASLD liver fibrosis metabolic syndrome genetic polymorphisms and drug therapy
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032025000101101&tlng=en

Similar Items

Applicability of Statins in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
by: Thaninee Prasoppokakorn
Published: (2025-01-01)

RENAL INJURY AND METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE IN PATIENTS WITH OBESITY
by: Kellyane Dias CARVALHO, et al.
Published: (2025-05-01)

ASSOCIATION BETWEEN ANXIETY AND DEPRESSION IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE (MASLD)
by: Eloyse Cristina BOTACIN, et al.
Published: (2024-07-01)

Liver Cell Mitophagy in Metabolic Dysfunction-Associated Steatotic Liver Disease and Liver Fibrosis
by: Jiaxin Chen, et al.
Published: (2024-06-01)

Hyperferritinemia and the Risk of Liver Fibrosis and Liver-Related Events in Patients with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease
by: Simona Cernea, et al.
Published: (2025-08-01)

Myosteatosis: Diagnosis, pathophysiology and consequences in metabolic dysfunction-associated steatotic liver diseaseKey points
by: Guillaume Henin, et al.
Published: (2024-02-01)

Effect of a Ketogenic Diet on Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) Progression: A Randomized Controlled Trial
by: Sakkarin Chirapongsathorn, et al.
Published: (2025-01-01)

Impact of cholecystectomy on Metabolic dysfunction-Associated Steatotic Liver Disease and metabolic syndrome: a 6-month prospective cohort study
by: Mohammad Hadi Bahri, et al.
Published: (2025-09-01)

Steatotic Liver Disease: Metabolic Dysfunction, Alcohol, or Both?
by: Katharina Staufer, et al.
Published: (2023-07-01)

Allyl nonanoate as a novel bile-derived biomarker in metabolic dysfunction-associated steatotic liver disease
by: Soo Hyeon Lee, et al.
Published: (2025-10-01)

Sequential Diagnostic Approach Using FIB-4 and ELF for Predicting Advanced Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease
by: Yeo-Wool Kang, et al.
Published: (2024-11-01)

Steatotic Liver Disease: New Nomenclature and Its Localization in the Russian Federation
by: K. L. Raikhelson, et al.
Published: (2024-05-01)

An overview of pathogenesis of metabolic dysfunction-associated steatotic liver disease
by: Shahid Habib, et al.
Published: (2024-11-01)

Diagnostic performance of FibroTouch® in assessing hepatic steatosis and fibrosis in patients with metabolic dysfunction-associated steatotic liver disease: An Asian experience
by: Thanikan Sukaram, et al.
Published: (2025-01-01)

A new name for an old problem. Metabolic dysfunction-associated steatotic liver disease - review of literature
by: Adrian Kruszewski, et al.
Published: (2024-07-01)

Editorial: Unraveling the links between nutrients and metabolic dysfunction-associated liver disease: insights and implications
by: Bruno Ramos-Molina, et al.
Published: (2024-11-01)

Metabolic dysfunction-associated steatotic liver disease: ferroptosis related mechanisms and potential drugs
by: Baoqiang Zhu, et al.
Published: (2023-11-01)

Circulating angiopoietin-like protein 8 (ANGPTL8) and steatotic liver disease related to metabolic dysfunction: an updated systematic review and meta-analysis
by: Farah Abdelhameed, et al.
Published: (2025-04-01)

TM6SF2 and PNPLA3: A potential dynamic duo?: Editorial on “TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD”
by: Andrea Caddeo, et al.
Published: (2025-01-01)

Critical appraisal of metabolic dysfunction-associated steatotic liver disease: Implication of Janus-faced modernity
by: Gi-Ae Kim, et al.
Published: (2023-10-01)

Metabolic associated steatotic liver disease misses fewer high-risk patients than metabolic associated fatty liver disease
by: Yu-Ming Cheng, et al.
Published: (2024-12-01)

Clinical impact of five cardiometabolic risk factors in metabolic dysfunction-associated steatotic liver disease (MASLD): Insights into regional and ethnic differences
by: Joo Hyun Oh, et al.
Published: (2024-04-01)

The correlation between heavy metal ions in blood and metabolic dysfunction-associated steatotic liver disease from 1999 to 2018 based on NHANES data
by: Haijun Ma, et al.
Published: (2025-01-01)

Validation of the American Association for the Study of Liver Disease/European Association for the Study of the Liver Multistep Screening Strategies for Metabolic Dysfunction-associated Steatotic Liver disease
by: Clémence Marie Canivet, et al.
Published: (2025-01-01)

Pathogenesis of metabolic dysfunction-associated steatotic liver disease and donor liver damage
by: Chuheng Gou, et al.
Published: (2025-12-01)

Low-dose valine attenuates diet-induced metabolic dysfunction-associated steatotic liver disease (MASLD) in mice by enhancing leptin sensitivity and modulating the gut microbiome
by: Felicianna, et al.
Published: (2024-12-01)

Risk of Hepatocellular Carcinoma by Steatotic Liver Disease and Its Newly Proposed Subclassification
by: Byeong Geun Song, et al.
Published: (2024-03-01)

Role of waist circumference, body mass index and high-sensitivity C-reactive protein in pediatric steatotic liver disease: A cross-sectional study
by: Qiaoling Wu, et al.
Published: (2025-01-01)

Unmet needs of metabolic dysfunction – Associated “fatty or steatotic” liver disease
by: Yu-Ming Cheng, et al.
Published: (2025-04-01)

Predictors of Significant Fibrosis Among People Living with HIV with Metabolic Dysfunction- Associated Steatotic Liver Disease
by: Thaninee Prasoppokakorn, et al.
Published: (2024-12-01)

Evaluation of the Potential Benefits of Trimetazidine in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Controlled Trial
by: Maha Youssif, et al.
Published: (2025-08-01)

Impact of steatotic liver disease subtypes, sarcopenia, and fibrosis on all-cause and cause-specific mortality: a 15.7-year cohort study
by: Yebei Liang, et al.
Published: (2025-02-01)

Mitochondrial Dysfunction-Associated Mechanisms in the Development of Chronic Liver Diseases
by: Madan Kumar Arumugam, et al.
Published: (2023-10-01)

Inhibiting Ferroptosis Prevents the Progression of Steatotic Liver Disease in Obese Mice
by: Gi Cheol Park, et al.
Published: (2024-10-01)

Predictive factors for metabolic syndrome in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)
by: Mohammad Alnees, et al.
Published: (2025-08-01)

Chronic Inflammation and Immune Dysregulation in Metabolic-Dysfunction-Associated Steatotic Liver Disease Progression: From Steatosis to Hepatocellular Carcinoma
by: Young-Min Jee, et al.
Published: (2025-05-01)

Genome-Wide DNA Methylation Markers Associated With Metabolic Liver Cancer
by: Samuel O. Antwi, et al.
Published: (2025-01-01)

Impact of myokines on chronic liver diseases: exploring the effects of metabolic dysfunction-associated steatotic liver disease (MASLD) on skeletal muscle. A narrative review
by: Francisco Aguirre, et al.
Published: (2025-07-01)

FLI and FIB-4 in diagnosing metabolic dysfunction-associated steatotic liver disease in primary care: High prevalence and risk of significant disease
by: Mário Reis Álvares-da-Silva, et al.
Published: (2025-01-01)

Association between periodontitis and mortality in participants with metabolic dysfunction-associated steatotic liver disease: results from NHANES
by: Zhaofu Zhang, et al.
Published: (2025-04-01)