GATA1 Gene Polymorphisms in Down Syndrome Patients

Objectives: Down syndrome (DS) patients have a 500 fold higher possibility of developing acute megakaryoblastic leukemia (AMKL), compared with the general population. GATA1 mutations, acquired in the early prenatal stages, contributes to leukemogenesis in AMKL and has been the explanation for the ca...

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發表在:	Central Asian Journal of Medical Sciences
Main Authors:	Kherlen Ponkhoon, Uranchimeg Bayarmagnai, Sarantuya Jav, Munkhtuya Tumurkhuu
格式:	Article
語言:	英语
出版:	Mongolian National University of Medical Sciences 2017-06-01
主題:	down syndrome gata1 transcription factor acute megakaryoblastic leukemia single nucleotide polymorphism
在線閱讀:	https://www.mongoliajol.info/index.php/CAJMS/article/view/2708