Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype
T-cell large granular lymphocyte (T-LGL) leukemia represents a clonal proliferation of cytotoxic T-cells which etiology has not been entirely elucidated. However, CD4+, CD4–,CD8–, CD4+, CD8+ cases have been described. The disease is usually characterized by cytopenias and a modest lymphocytosis. The...
| Published in: | Clinics and Practice |
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| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-06-01
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| Subjects: | |
| Online Access: | https://www.clinicsandpractice.org/index.php/cp/article/view/320 |
| _version_ | 1852738941078208512 |
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| author | Panagiota K. Petsa Achilleas Karamoutsios Lefkothea Dova Leonidas Benetatos Asimina Petsiou Nikolaos Kolaitis Antonis Georgopoulos Georgios Vartholomatos |
| author_facet | Panagiota K. Petsa Achilleas Karamoutsios Lefkothea Dova Leonidas Benetatos Asimina Petsiou Nikolaos Kolaitis Antonis Georgopoulos Georgios Vartholomatos |
| author_sort | Panagiota K. Petsa |
| collection | DOAJ |
| container_title | Clinics and Practice |
| description | T-cell large granular lymphocyte (T-LGL) leukemia represents a clonal proliferation of cytotoxic T-cells which etiology has not been entirely elucidated. However, CD4+, CD4–,CD8–, CD4+, CD8+ cases have been described. The disease is usually characterized by cytopenias and a modest lymphocytosis. The majority of patients with T-LGL leukemia remains asymptomatic for a long period and will require treatment later during the course of their disease. Hereby we describe a case of T-LGL leukemia diagnosed by flow cytometry, which presented indolent course and required no treatment so far. |
| format | Article |
| id | doaj-art-e8934a83dab7444b8ca9dd52cd046aef |
| institution | Directory of Open Access Journals |
| issn | 2039-7275 2039-7283 |
| language | English |
| publishDate | 2012-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-e8934a83dab7444b8ca9dd52cd046aef2025-08-19T21:05:35ZengMDPI AGClinics and Practice2039-72752039-72832012-06-012310.4081/cp.2012.e68204Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotypePanagiota K. Petsa0Achilleas Karamoutsios1Lefkothea Dova2Leonidas Benetatos3Asimina Petsiou4Nikolaos Kolaitis5Antonis Georgopoulos6Georgios Vartholomatos7Laboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaLaboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaLaboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaLaboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaLaboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaLaboratory of Hematology, University Hospital of IoanninaGeneral Hospital of Corfu, Laboratory of Hematology, CorfuLaboratory of Hematology, Unit of Molecular Biology, University Hospital of IoanninaT-cell large granular lymphocyte (T-LGL) leukemia represents a clonal proliferation of cytotoxic T-cells which etiology has not been entirely elucidated. However, CD4+, CD4–,CD8–, CD4+, CD8+ cases have been described. The disease is usually characterized by cytopenias and a modest lymphocytosis. The majority of patients with T-LGL leukemia remains asymptomatic for a long period and will require treatment later during the course of their disease. Hereby we describe a case of T-LGL leukemia diagnosed by flow cytometry, which presented indolent course and required no treatment so far.https://www.clinicsandpractice.org/index.php/cp/article/view/320large granular lymphocytesT-LGL leukemiaT cell receptorflow cytometry. |
| spellingShingle | Panagiota K. Petsa Achilleas Karamoutsios Lefkothea Dova Leonidas Benetatos Asimina Petsiou Nikolaos Kolaitis Antonis Georgopoulos Georgios Vartholomatos Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype large granular lymphocytes T-LGL leukemia T cell receptor flow cytometry. |
| title | Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype |
| title_full | Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype |
| title_fullStr | Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype |
| title_full_unstemmed | Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype |
| title_short | Asymptomatic T-cell large granular lymphocyte leukemia with an unusual immunophenotype |
| title_sort | asymptomatic t cell large granular lymphocyte leukemia with an unusual immunophenotype |
| topic | large granular lymphocytes T-LGL leukemia T cell receptor flow cytometry. |
| url | https://www.clinicsandpractice.org/index.php/cp/article/view/320 |
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