Albumin-Keratin Casts Obstruct Renal Tubular and Vascular Lumens Following Kidney Ischemia

Introduction: We have recently reported that in ischemic acute kidney injury (AKI), red blood cell (RBC) trapping causes fluid extravasation from the congested capillary circulation and subsequent toxic injury to the surrounding tubules. The goal of this study was to identify the cause of the obstru...

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Bibliographic Details
Published in:	Kidney International Reports
Main Authors:	Martina Bryant, Olivia Boykin, Olivia Mosley, Angela Ajith, Oliver Oglesby, Konstantin Kurzin, Carlee Harris, Sadaf Husan, Daniela Dokam, Sarah R. McLarnon, Jingping Sun, Brendan Marshall, Amanda Barrett, Aaron Polichnowski, Wendy B. Bollag, David Mattson, Paul M. O’Connor
Format:	Article
Language:	English
Published:	Elsevier 2026-04-01
Subjects:	acute kidney injury casts cytokeratin ischemia-reperfusion red blood cell trapping
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024926025878

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