Specific necroptosis inhibitor-1(Nec-1) attenuates glial scar formation in rat models with spinal cord injury

Objective To observe the effect of necroptosis inhibitor-1(Nec-1) on glial scar formation in rats with spinal cord injury and its mechanism. Methods The rats were randomly divided into sham group, model group (falling method) and RIPK1 inhibitor Nec-1 group (10 μmol/L Nec-1 10μL was injected into la...

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Bibliographic Details
Published in:	Jichu yixue yu linchuang
Main Author:	CHEN Sheng, WANG Chun-ming, YAN Xue-fei, MAO Yuan-qing
Format:	Article
Language:	Chinese
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-01-01
Subjects:	spinal cord injury\|glial scar\|necroptosis inhibitor-1(nec-1)\|cathepsin b
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-94.pdf

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