Mechanisms of drug resistance to immune checkpoint inhibitors in non-small cell lung cancer

Immune checkpoint inhibitors (ICIs) in the form of anti-CTLA-4 and anti-PD-1/PD-L1 have become the frontier of cancer treatment and successfully prolonged the survival of patients with advanced non-small cell lung cancer (NSCLC). But the efficacy varies among different patient population, and many p...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Kexun Zhou, Shuo Li, Yi Zhao, Ke Cheng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Subjects:	immunotherapy resistance mechanism tumor microenvironment lung cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1127071/full