探讨Fas/FasL的表达与大肠癌发展及转移的关系

【目的】探讨Fas/FasL在大肠癌组织细胞的表达以及它们与肿瘤的发展及转移的关系。【方法】应用免疫组化(SABC)法对41例(包括各个不同Dukes分期)的大肠癌组织以及正常大肠组织的Fas/FasL进行检测。【结果】大肠癌组织Fas阳性率为48.8%,低于正常大肠黏膜组织的Fas阳性率92.7%(P<0.01)。大肠癌组织FasL阳性率为53.7%,高于正常大肠黏膜组织的FasL阳性率4.9%(P<0.01)。在不同分期的大肠癌组织中,Fas阳性率分别为:A期87.5%,B期66.7%,C期25.0%,D期21.2%。而FasL阳性率分别为:A期25.0%,B期33.3%,C期...

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Bibliographic Details
Published in:	Zhongshan Daxue xuebao. Yixue kexue ban
Main Authors:	黄文生, 彭慧, 谭进富, 谭敏
Format:	Article
Language:	Chinese
Published:	Editorial Office of Journal of Sun Yat-sen University 2008-01-01
Subjects:	结直肠肿瘤细胞凋亡 Fas FasL
Online Access:	http://xuebaoyx.sysu.edu.cn/zh/article/43581908/

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