A scoping review of imatinib-induced testicular toxicity and male fertility impairment

BackgroundImatinib, the first-generation tyrosine kinase inhibitor (TKI), has been widely adopted as frontline therapy for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). Growing evidence indicates potential gonadotoxic effects, raising concerns about its long-term impact...

書誌詳細
出版年:	Frontiers in Endocrinology
主要な著者:	Xia Ji, Mohd Faizal Ahmad, Mohd Helmy Mokhtar, XiaoYing He, Abdul Kadir Abdul Karim
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2026-05-01
主題:	fertility preservation imatinib mesylate spermatogenesis testicular diseases testis/drug effects
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1811653/full

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