Modulatory effects of perindopril on cisplatin-induced nephrotoxicity in mice: Implication of inflammatory cytokines and caspase-3 mediated apoptosis

Cisplatin-induced nephrotoxicity limits its anticancer effectiveness, thus this study’s aim was to assess the potential modulatory effect of perindopril on cisplatin-induced nephrotoxicity and to elucidate the possible underlying mechanisms. Renal dysfunction was induced in mice by a single injectio...

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Bibliographic Details
Published in:	Acta Pharmaceutica
Main Authors:	Aljuhani Naif, Ismail Raed S., El-Awady Mohammed S., Hassan Memy H.
Format:	Article
Language:	English
Published:	Sciendo 2020-12-01
Subjects:	perindopril cisplatin nephrotoxicity oxidative stress apoptosis inflammation
Online Access:	https://doi.org/10.2478/acph-2020-0033

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