Dynamics of Onset and Progression in Amyotrophic Lateral Sclerosis

This review focuses on the complexities of amyotrophic lateral sclerosis (ALS) onset, highlighting the insidious nature of the disease and the challenges in defining its precise origin and early pathogenic mechanisms. The clinical presentation of ALS is characterised by progressive muscle weakness a...

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Bibliographic Details

Published in:	Brain Sciences
Main Authors:	Michael Swash, Mamede de Carvalho
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Subjects:	amyotrophic lateral sclerosis lower motor neuron onset progression upper motor neuron treatment
Online Access:	https://www.mdpi.com/2076-3425/15/6/601