The Use of Low-Dose Methadone as Add-On to Ongoing Opioid Treatment in Palliative Cancer Care—An Underrated Treatment?

The aim of this review is to summarize the current knowledge of low-dose methadone treatment in palliative cancer care. In Sweden, methadone is quite common in specialized palliative care, where almost a tenth of patients are prescribed this drug. Negative attitudes towards methadone do not seem to...

Full description

Bibliographic Details
Published in:	Life
Main Author:	Per Fürst
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	methadone pain palliative cancer opioid
Online Access:	https://www.mdpi.com/2075-1729/12/5/679

Similar Items

Reply to “A better interpretation of data regarding the opioid switching to methadone”
by: Haiying Ding, et al.
Published: (2023-06-01)

Pharmacy-based methadone treatment in the US: views of pharmacists and opioid treatment program staff
by: Li-Tzy Wu, et al.
Published: (2023-09-01)

Old Drug, New Pain. Roles and Challenges of Methadone Therapy in Pediatric Palliative Care: A Systematic Review
by: Francesca Benedetti, et al.
Published: (2022-05-01)

Identification of Factors Contributing to Methadone-Induced Daytime Sleepiness in Cancer Patients and Proposal of the Conversion Ratio from Other Opioids to Oral Methadone: A Retrospective Cohort Study
by: Miho Takemura, et al.
Published: (2023-07-01)

Methadone rotation versus other opioid rotation for refractory cancer induced bone pain: protocol of an exploratory randomised controlled open-label study
by: Natasha Michael, et al.
Published: (2023-04-01)

Opioid Substitution: More than Only Methadone!
by: M. Torrens
Published: (2022-06-01)

Regular, low-dose methadone for reducing breathlessness in people experiencing or at risk of neurotoxic effects from morphine: A single-center case series
by: Piotr Z. Sobanski, et al.
Published: (2022-12-01)

Patient perspectives on community pharmacy administered and dispensing of methadone treatment for opioid use disorder: a qualitative study in the U.S.
by: Li-Tzy Wu, et al.
Published: (2023-08-01)

Perceived barriers to methadone maintenance treatment among Iranian opioid users
by: Maryam Khazaee-Pool, et al.
Published: (2018-06-01)

Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment
by: Peng-Wei Wang, et al.
Published: (2017-12-01)

Relationship between cold pressor pain-sensitivity and sleep quality in opioid-dependent males on methadone treatment
by: Zalina Zahari, et al.
Published: (2015-04-01)

Ultralow-Dose Adjunctive Methadone with Slow Titration, Considering Long Half-Life, for Outpatients with Cancer-Related Pain
by: Srini Chary, et al.
Published: (2020-07-01)

Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone
by: Webster LR, et al.
Published: (2018-10-01)

A Preliminary Study of Sexual Dysfunction in Male Opioid-Dependants under Methadone Maintenance Treatment
by: Masoudeh Babakhanian, et al.
Published: (2011-08-01)

Opioid treatment program prescribing of methadone with community pharmacy dispensing: Pilot study of feasibility and acceptability
by: Robert K. Brooner, et al.
Published: (2022-06-01)

Methadone Conversion Using a 3-Day Switch Strategy in Patients with Cancer on High-Dose Opioids: A Retrospective Study
by: Lei Lei, et al.
Published: (2024-09-01)

Optimizing methadone dose adjustment in patients with opioid use disorder
by: Po-Shen Liu, et al.
Published: (2024-01-01)

Effectiveness of Relapse Prevention Cognitive Behavioral Model in Opioid Dependent Patients Participating in the Methadone Maintenance Treatment in Iran
by: Fatemeh Rajati, et al.
Published: (2013-08-01)

Methadone‐induced hypoglycemia: A case report
by: Ramin Malboosbaf, et al.
Published: (2023-01-01)

Acupuncture for Opioid Dependence Patients Receiving Methadone Maintenance Treatment: A Network Meta-Analysis
by: Hao Wen, et al.
Published: (2021-12-01)

Opioid Use Disorder Induces Oxidative Stress and Inflammation: The Attenuating Effect of Methadone Maintenance Treatment
by: Ali Salarian, et al.
Published: (2018-02-01)

Buprenorphine/naloxone versus methadone opioid rotation in patients with prescription opioid use disorder and chronic pain: study protocol for a randomized controlled trial
by: Hannah Ellerbroek, et al.
Published: (2022-09-01)

Comparing quality of life methadone and buprenorphine for opioid substitution treatment in Iran
by: Ahmad Nemati, et al.
Published: (2025-08-01)

Chart Review and Practical Recommendations for the Use of Methadone as an Alternative to Opioid Rotation in the Management of Cancer-Related Pain
by: Arunangshu Ghoshal, et al.
Published: (2024-12-01)

Impact of COVID-19-related methadone regulatory flexibilities: views of state opioid treatment authorities and program staff
by: Shannon Gwin Mitchell, et al.
Published: (2023-10-01)

Methadone Maintenance Therapy (MMT) and Alternatives in Opioid Use Disorder: Reviewing the latest advancements, outcomes, and challenges in substitutional therapy for opioid addiction - literature review
by: Karolina Koszyczarek, et al.
Published: (2024-02-01)

Comparison of low-dose ketamine to methadone for postoperative pain in opioid addicts: a randomized clinical trial
by: Elham Bakhtiari, et al.
Published: (2024-07-01)

A better interpretation of data regarding the opioid switching to methadone
by: Sebastiano Mercadante
Published: (2023-06-01)

The role of methadone in cardiac surgery for management of postoperative pain
by: Jordan N. Edwards, et al.
Published: (2024-06-01)

Methadone switching for refractory cancer pain
by: Haiying Ding, et al.
Published: (2022-11-01)

Effectiveness of take-home methadone treatment among patients with opioid use disorders during COVID-19: A systematic review
by: Shabnam Naher, et al.
Published: (2024-09-01)

Evaluation of urinary trace element levels in patients with opioid use disorder undergoing methadone treatment in western Iran
by: Samaneh Nakhaee, et al.
Published: (2024-03-01)

Technical violations and infractions are drivers of disengagement from methadone treatment among people with opioid use disorder discharged from Connecticut jails 2014–2018
by: Phillip Marotta, et al.
Published: (2023-07-01)

The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy
by: Leen Naji, et al.
Published: (2017-03-01)

Methadone and Buprenorphine as Medication for Addiction Treatment Diversely Affect Inflammation and Craving Depending on Their Doses
by: Christonikos Leventelis, et al.
Published: (2025-03-01)

Risk factors for poor treatment outcomes among opioid-dependent clients taking methadone in Mombasa, Kenya
by: Nassoro Mwanyalu, et al.
Published: (2024-06-01)

The Influence of a Single Therapeutic Dose of Methadone on Selected Auditory Functions in Patients Addicted to Opioids and Undergoing Substitution Therapy – a Preliminary Study
by: Emilia TARNOWSKA, et al.
Published: (2018-01-01)

Buprenorphine‐naloxone, buprenorphine, and methadone throughout pregnancy in maternal opioid use disorder
by: Minna M. Kanervo, et al.
Published: (2023-03-01)

Methadone Treatment Gap in Tennessee and How Medication Units Could Bridge the Gap: A Review
by: Joanna Risby, et al.
Published: (2023-08-01)

The Use of Opioids in an Acute Palliative Care Unit to Re-assess Prescriptions
by: Sebastiano Mercadante, et al.
Published: (2025-03-01)