Local autologous platelet rich plasma injection combined with platelet rich fibrin filling as the main treatment for refractory wounds: A case series

Refractory wounds are a major global health problem that not only affects the quality of life, but also causes significant physical, psychological and economic burdens. How to promote wound healing has become the main goal of clinicians. To evaluate the safety and efficacy of local autologous platel...

Full description

Bibliographic Details
Published in:	Frontiers in Surgery
Main Authors:	Xiang Liu, Xiangjun Li, Wei Wei, Xiang Zhang, Zheng Fang, Zixiu Chen, Pingxiang Chen, Haihong Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	platelet rich plasma platelet rich fibrin refractory wounds autologous wound repair
Online Access:	https://www.frontiersin.org/articles/10.3389/fsurg.2022.1003691/full

Similar Items

Autologous platelet-rich fibrin promotes wound healing in cats
by: Anamika Changrani-Rastogi, et al.
Published: (2023-05-01)

Effect of fresh autologous platelet-rich fibrin in the treatment of chronic sinus wounds
by: LIU Shasha*, XUE Lili, SUN Rong, LIU Yahui *
Published: (2025-09-01)

Biological characterization of an injectable platelet-rich fibrin mixture consisting of autologous albumin gel and liquid platelet-rich fibrin (Alb-PRF)
by: Masako Fujioka-Kobayashi, et al.
Published: (2021-01-01)

Platelet-rich fibrin – A narrative review
by: Shankar Shanmugam, et al.
Published: (2023-01-01)

Management of canine wounds using platelet‐rich fibrin (PRF) biomaterial. A case series report
by: Carla S. Soares, et al.
Published: (2024-05-01)

Platelet-rich fibrin (PRF) as an autologous biomaterial after an endodontic surgery: Case reports
by: Kavitha Anantula, et al.
Published: (2016-01-01)

The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites
by: Esra Ercan
Published: (2018-12-01)

Platelet-rich fibrin: Basics of biological actions and protocol modifications
by: Pavlovic Voja, et al.
Published: (2021-03-01)

Effect of platelet‐rich plasma and platelet‐rich fibrin on healing of burn wound with dual‐species biofilm
by: Wen‐Dan Li, et al.
Published: (2025-03-01)

Autologous Matrix of Platelet-Rich Fibrin in Wound Care Settings: A Systematic Review of Randomized Clinical Trials
by: Chayane Karla Lucena de Carvalho, et al.
Published: (2020-05-01)

Comparative evaluation of antimicrobial efficacy of platelet-rich plasma, platelet-rich fibrin, and injectable platelet-rich fibrin on the standard strains of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans
by: Prabhdeep Kour, et al.
Published: (2018-01-01)

Platelet-rich fibrin: Current trends in periodontal regeneration
by: Deepa Sara John, et al.
Published: (2023-09-01)

Evaluation of the use of autologous platelet-rich fibrin in myringoplasty operation
by: Heba Abdelreheem Aboelnaga, et al.
Published: (2022-10-01)

Comparative study using autologous platelet-rich fibrin and titanium prepared platelet-rich fibrin in the treatment of infrabony defects: An in vitro and in vivo study
by: Dipika Kalyan Mitra, et al.
Published: (2019-01-01)

In vitro comparison of the effects of titanium-prepared platelet-rich fibrin and leukocyte platelet-rich fibrin on osteoblast behavior and their gen expression
by: Melike Baygın, et al.
Published: (2024-12-01)

The Use of Autologous Platelet Rich Fibrin Membrane as a Second Layer in Snodgrass Repair of Distal Hypospadias
by: Ahmed Shaker Fouad Al-Awadi, et al.
Published: (2021-04-01)

Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts
by: Laura Baca-Gonzalez, et al.
Published: (2022-10-01)

Effects of autologous platelet-rich plasma combined with negative pressure wound therapy for chronic refractory wounds: a Meta-analysis
by: Wenda FU, et al.
Published: (2023-02-01)

Autologous platelet-rich fibrin enhances skin wound healing in a feline trauma model
by: Shuai Zhang, et al.
Published: (2024-11-01)

Results of the use of human platelet-rich fibrin membrane applied on colorrhaphy in nourished and malnourished rats
by: Fábio Henrique de Oliveira, et al.
Published: (2024-11-01)

The treatment of refractory wounds with apheresis platelet-rich plasma
by: Ruixian LUO, et al.
Published: (2024-09-01)

Evaluation of injectable platelet-rich fibrin produced by a simple twice-centrifugation method combined with vacuum sealing drainage technology in the treatment of chronic refractory wounds
by: Xin Xue, et al.
Published: (2022-10-01)

Evaluation of Platelet-rich Fibrin Matrix Dressings in Patients with Chronic Nonhealing Leg Ulcers
by: Shishira R. Jartarkar, et al.
Published: (2025-01-01)

Effects of Platelet-Rich Fibrin on In Vitro Periodontal Ligament Cell Functions
by: Pablo Cores Ziskoven, et al.
Published: (2025-09-01)

Autologous Platelet-Rich Fibrin to Treat Difficult Nonhealing Diabetic Foot Wounds with Exposed Bone – A Case Report of This Safe, Effective, and Economical Method
by: Riju Ramachandran Menon, et al.
Published: (2020-10-01)

Platelet-rich fibrin as an autologous biomaterial for bone regeneration: mechanisms, applications, optimization
by: Kewen Jia, et al.
Published: (2024-04-01)

Histological analysis of bone three months after the treatment of oroantral communication with autologous platelet-rich fibrin - a case series
by: Rebić Kristina, et al.
Published: (2023-01-01)

Biostimulation effect of platelet-rich fibrin augmented with decellularized bovine pericardium on full-thickness cutaneous wound healing in Donkeys (Equus asinus)
by: Mohammed Albahrawy, et al.
Published: (2023-09-01)

Clinical and Radiographic Outcomes of Autologous Platelet-Rich Products in Regenerative Endodontics: A Systematic Review and Meta-Analysis
by: Raewyn Huang, et al.
Published: (2025-05-01)

Treatment of non-healing sternum wound after open-heart surgery with allogenic platelet-rich plasma and fibrin glue-preliminary outcomes
by: Mohammad Abbasi Tashnizi, et al.
Published: (2013-09-01)

Vivostat Platelet-Rich Fibrin<sup>®</sup> for Complicated or Chronic Wounds—A Pilot Study
by: Andreas Bayer, et al.
Published: (2020-08-01)

Clinical observation of autologous platelet rich fibrin assisted revascularization of mature permanent teeth
by: Zhaojun Wu, et al.
Published: (2023-03-01)

Comparative analysis of cytokine profiles in canine injectable platelet-rich fibrin and platelet-rich plasma
by: Ekkapol Akaraphutiporn, et al.
Published: (2025-12-01)

Development of a super-hydrophilic anaerobic tube for the optimization of platelet-rich fibrin
by: Yan Wei, et al.
Published: (2024-12-01)

A Randomized Controlled Study Comparing Albumin-Enriched Platelet-Rich Fibrin and Conventional Platelet-Rich Fibrin for the Treatment of Intrabony Defects
by: Sharmila Kumari, et al.
Published: (2025-06-01)

Effectiveness of Silicon Platelet-Rich Fibrin and Autologous Bone on Bone Regeneration in Rabbit Calvarian Defects: A Radiological and Histological Study
by: Argimiro Hernández-Suarez, et al.
Published: (2021-04-01)

Platelet-Rich Therapies in Hernia Repair: A Comprehensive Review of the Impact of Platelet Concentrates on Mesh Integration in Hernia Management
by: Elissavet Anestiadou, et al.
Published: (2024-07-01)

Platelet rich fibrin as a gingival tissue regeneration enhancer
by: Bianca Nausica Petrescu, et al.
Published: (2021-01-01)

Platelet-rich fibrin is the first-line treatment option for periodontal regeneration
by: Ni-Yu Su, et al.
Published: (2017-09-01)

Canine-Origin Platelet-Rich Fibrin as an Effective Biomaterial for Wound Healing in Domestic Cats: A Preliminary Study
by: Carla S. Soares, et al.
Published: (2021-09-01)