Clinical significance of antibodies to the phosphatidylserine/prothrombin complex

Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune th...

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Bibliographic Details
Published in:Современная ревматология
Main Authors: T. M. Reshetnyak, F. A. Cheldieva, M. V. Cherkasova, A. M. Lila
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2022-05-01
Subjects:
antiphospholipid antibodies
antiphospholipid syndrome
systemic lupus erythematosus
thrombosis
obstetric pathology
antibodies to prothrombin
antibodies to the phosphatidylserine/prothrombin complex
Online Access:https://mrj.ima-press.net/mrj/article/view/1279
Description
Summary:Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune thrombophilia continues to be debated. The review presents literature data on the study of antibodies to prothrombin and the phosphatidylserine/prothrombin complex in patients with systemic lupus erythematosus and APS.
ISSN:1996-7012
2310-158X

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