Clinical significance of antibodies to the phosphatidylserine/prothrombin complex

Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune th...

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Published in:Современная ревматология
Main Authors: T. M. Reshetnyak, F. A. Cheldieva, M. V. Cherkasova, A. M. Lila
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2022-05-01
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1279
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author T. M. Reshetnyak
F. A. Cheldieva
M. V. Cherkasova
A. M. Lila
author_facet T. M. Reshetnyak
F. A. Cheldieva
M. V. Cherkasova
A. M. Lila
author_sort T. M. Reshetnyak
collection DOAJ
container_title Современная ревматология
description Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune thrombophilia continues to be debated. The review presents literature data on the study of antibodies to prothrombin and the phosphatidylserine/prothrombin complex in patients with systemic lupus erythematosus and APS.
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spelling doaj-art-eaf22f5cc1584fb592f7d17dc6d7b2e82025-08-20T03:59:54ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2022-05-01162818610.14412/1996-7012-2022-2-81-862469Clinical significance of antibodies to the phosphatidylserine/prothrombin complexT. M. Reshetnyak0F. A. Cheldieva1M. V. Cherkasova2A. M. Lila3V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional EducationV.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional EducationV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional EducationClassical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune thrombophilia continues to be debated. The review presents literature data on the study of antibodies to prothrombin and the phosphatidylserine/prothrombin complex in patients with systemic lupus erythematosus and APS.https://mrj.ima-press.net/mrj/article/view/1279antiphospholipid antibodiesantiphospholipid syndromesystemic lupus erythematosusthrombosisobstetric pathologyantibodies to prothrombinantibodies to the phosphatidylserine/prothrombin complex
spellingShingle T. M. Reshetnyak
F. A. Cheldieva
M. V. Cherkasova
A. M. Lila
Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
antiphospholipid antibodies
antiphospholipid syndrome
systemic lupus erythematosus
thrombosis
obstetric pathology
antibodies to prothrombin
antibodies to the phosphatidylserine/prothrombin complex
title Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
title_full Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
title_fullStr Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
title_full_unstemmed Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
title_short Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
title_sort clinical significance of antibodies to the phosphatidylserine prothrombin complex
topic antiphospholipid antibodies
antiphospholipid syndrome
systemic lupus erythematosus
thrombosis
obstetric pathology
antibodies to prothrombin
antibodies to the phosphatidylserine/prothrombin complex
url https://mrj.ima-press.net/mrj/article/view/1279
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