ADuLT: An efficient and robust time-to-event GWAS

Abstract Proportional hazards models have been proposed to analyse time-to-event phenotypes in genome-wide association studies (GWAS). However, little is known about the ability of proportional hazards models to identify genetic associations under different generative models and when ascertainment i...

Full description

Bibliographic Details
Published in:	Nature Communications
Main Authors:	Emil M. Pedersen, Esben Agerbo, Oleguer Plana-Ripoll, Jette Steinbach, Morten D. Krebs, David M. Hougaard, Thomas Werge, Merete Nordentoft, Anders D. Børglum, Katherine L. Musliner, Andrea Ganna, Andrew J. Schork, Preben B. Mortensen, John J. McGrath, Florian Privé, Bjarni J. Vilhjálmsson
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-09-01
Online Access:	https://doi.org/10.1038/s41467-023-41210-z

Similar Items

Publisher Correction: Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
by: Clara Albiñana, et al.
Published: (2024-02-01)

Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
by: Clara Albiñana, et al.
Published: (2023-02-01)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
by: Clara Albiñana, et al.
Published: (2023-08-01)

Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders
by: Trine Munk-Olsen, et al.
Published: (2023-11-01)

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
by: Ron Nudel, et al.
Published: (2022-08-01)

Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
by: Vivek Appadurai, et al.
Published: (2023-01-01)

Microsatellite based genetic characterization of Kanni Adu, Kodi Adu and Salem Black goats of Tamil Nadu
by: M JEYAKUMAR, et al.
Published: (2014-09-01)

Population-representative inference for primary and secondary outcomes in extended case-cohort designs
by: Theresa Wimberley, et al.
Published: (2025-10-01)

Isolation and characterization of Brochothrix phage ADU4
by: Abdulkerim Karaynir, et al.
Published: (2022-11-01)

The contribution of general medical conditions to the non-fatal burden of mental disorders: register-based cohort study in Denmark
by: Nanna Weye, et al.
Published: (2022-11-01)

Liposomal Delivery of MIW815 (ADU-S100) for Potentiated STING Activation
by: Nan Ji, et al.
Published: (2023-02-01)

Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study
by: Tina Nørgaard Munch, et al.
Published: (2021-04-01)

Perkawinan Adu Wuwung dalam Pandangan Hukum Adat dan Hukum Islam
by: Khyatudin Khyatudin, et al.
Published: (2020-08-01)

Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
by: Ron Nudel, et al.
Published: (2021-11-01)

Correction: Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
by: Ron Nudel, et al.
Published: (2023-09-01)

МНОГОКАНАЛЬНАЯ СИСТЕМА СБОРА И ОБРАБОТКИ ИНФОРМАЦИИ НА БАЗЕ КОНТРОЛЛЕРА ADuC7061
by: А. А. Дьякова, et al.
Published: (2014-08-01)

Da ɗan gari akan ci gari: nazarin al'adu a al’ummar Hausawa
by: Aliyu Mu’azu
Published: (2006-12-01)

Ross for Valve replacement In AduLts (REVIVAL) pilot trial: rationale and design of a randomised controlled trial
by: Serban Stoica, et al.
Published: (2021-09-01)

Assessment of Village Readiness for Electronic Citizen Complaint Services (e-AduMas) Using COBIT 4.1
by: Doddy Ferdiansyah, et al.
Published: (2023-12-01)

<em>In Vivo</em> Histamine Optical Nanosensors
by: Heather A. Clark, et al.
Published: (2012-08-01)

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease.
by: Christian M Hagen, et al.
Published: (2018-01-01)

The impact of fibrotic diseases on global mortality from 1990 to 2019
by: Henricus A. M. Mutsaers, et al.
Published: (2023-11-01)

Comparing Methods for Missing Paternal Linkages in Administrative Data
by: Amani Hamad, et al.
Published: (2024-09-01)

<b>Compostos fenólicos e atividade antioxidante de <i>Leiothrix flavescens</i> (Bong.) Ruhland (Eriocaulaceae)</b>
by: M. A. SILVA, et al.
Published: (2009-01-01)

Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study
by: Oleguer Plana-Ripoll, et al.
Published: (2022-06-01)

Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study.
by: Oleguer Plana-Ripoll, et al.
Published: (2022-06-01)

MODEL INVESTIGASI KELOMPOK DENGAN TEKNIK ADU ARGUMEN SEBAGAI UPAYA PENINGKATAN KOMPETENSI PEDAGOGIK CALON GURU BAHASA INDONESIA
by: Ida Zulaeha
Published: (2015-02-01)

IZMENENIYa SUTOChNOGO PROFILYa ADU BOL'NYKh OSTEOARTROZOM V ZAVISIMOSTI OT NALIChIYa ARTERIAL'NOY GIPERTONII
by: R G Kamalova, et al.
Published: (2005-06-01)

Cyto-IL-15 synergizes with the STING agonist ADU-S100 to eliminate prostate tumors and confer durable immunity in mouse models
by: Efthymia Papaevangelou, et al.
Published: (2023-07-01)

<b>EXPEDIENTE</b>
by: RODRIGO SILVESTRE
Published: (2010-06-01)

<b>EXPEDIENTE</b>
by: Rodrigo Silvestre
Published: (2011-05-01)

<b>EXPEDIENTE</b>
by: Rodrigo Silvestre
Published: (2011-05-01)

Thiadiazines, <em>N</em>,<em>N</em>-Heterocycles of Biological Relevance
by: Hortensia Rodríguez, et al.
Published: (2012-06-01)

<i>In Vitro</i> Micropropagation of the Medicinal Plant <i>Physalis angulata</i> L.
by: Owk ANIEL KUMAR, et al.
Published: (2016-06-01)

Sauyunan: Solidaritas Masyarakat dalam Proses Pelaksanaan Tradisi Rempug Tarung Adu Tomat di Kampung Cikareumbi Kabupaten Bandung Barat
by: Mirna Nur Alia Abdullah, et al.
Published: (2022-12-01)

Anion- or Cation-Exchange Membranes for NaBH<sub>4</sub>/H<sub>2</sub>O<sub>2 </sub>Fuel Cells?
by: César A. C. Sequeira, et al.
Published: (2012-07-01)

<b>Apresentação</b> - doi: 10.4025/dialogos.v10i1.107 <b>Foreword</b> - doi: 10.4025/dialogos.v10i1.107 Presentación
by: Sidnei J. Munhoz
Published: (2010-05-01)

<b>Determinação de massa fresca, massa seca, água e cinzas totais de folhas de <i>Cissus verticillata</i> (L.) Nicolson & C. E. Jarvis subsp. <i>verticillata</i> e avaliação do processo de secagem em estufa com ventilação forçada</b>
by: T. V. BRAGA, et al.
Published: (2009-01-01)

<b> <i>Brosimum gaudichaudii</i> Trecul (Moraceae): da planta ao medicamento </b>
by: G. L. POZETTI
Published: (2009-01-01)

Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine <em>Ostreae </em><em>c</em><em>oncha</em>
by: Hong-Bing Liu, et al.
Published: (2012-05-01)