16 kDa vasoinhibin binds to integrin alpha5 beta1 on endothelial cells to induce apoptosis

Many functions of vasoinhibins have been reported, but its receptor has not been clarified yet. Vasoinhibins, 11–18 kDa N-terminal fragments of prolactin, have anti-angiogenic activity and act on endothelial cells to induce apoptosis and to inhibit migration and proliferation, which are opposite to...

Full description

Bibliographic Details
Published in:Endocrine Connections
Main Authors: Kazunori Morohoshi, Ryo Mochinaga, Tsukasa Watanabe, Ryojun Nakajima, Toshio Harigaya
Format: Article
Language:English
Published: Bioscientifica 2018-04-01
Subjects:
Online Access:http://www.endocrineconnections.com/content/7/5/630.full