Ehlers-Danlos Syndrome and Fibromyalgia: Beyond Pain and Fatigue
Introduction: Ehlers-Danlos syndrome (EDS) is a genetic disorder that affects the connective tissue. Hypermobile subtype (hEDS), which is the most common, is characterized by joint hyperlaxity, diffuse generalized pain, and chronic fatigue. Meanwhile, fibromyalgia is a pain regulation disorder of ch...
| Published in: | Revista Salud Bosque |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Universidad El Bosque
2024-08-01
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| Subjects: | |
| Online Access: | https://revistas.unbosque.edu.co/index.php/RSB/article/view/4489 |
| Summary: | Introduction: Ehlers-Danlos syndrome (EDS) is a genetic disorder that affects the connective tissue. Hypermobile subtype (hEDS), which is the most common, is characterized by joint hyperlaxity, diffuse generalized pain, and chronic fatigue. Meanwhile, fibromyalgia is a pain regulation disorder of chronic, widespread musculoskeletal pain, fatigue, cognitive disturbance, psychiatric and multiple somatic symptoms.
Objective: To examine the similarities and differences between hEDS, fibromyalgia and highlight the importance of their proper diagnosis and treatment.
Methods: A systematic search of PubMed and Scopus databases was performed for all English - Spanish language studies published between 2013 and May 2023. Two reviewers independently selected studies, extracted data and applied quality criteria. Study quality was assessed using PRISMA and a synthesis of the best evidence was obtained.
Results: A total of 20 studies met the criteria and were therefore analyzed.
Conclusion: Diagnosing EDS and fibromyalgia can be challenging in medical practice as their clinical manifestations can overlap, and they may even coexist in the same patient.
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| ISSN: | 2248-5759 2322-9462 |