Targeting Ubiquitin-Proteasome Pathway by Natural Products: Novel Therapeutic Strategy for Treatment of Neurodegenerative Diseases

Misfolded proteins are the main common feature of neurodegenerative diseases, thereby, normal proteostasis is an important mechanism to regulate the neural survival and the central nervous system functionality. The ubiquitin-proteasome system (UPS) is a non-lysosomal proteolytic pathway involved in...

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Bibliographic Details
Published in:	Frontiers in Physiology
Main Authors:	Saeideh Momtaz, Zahra Memariani, Fardous F. El-Senduny, Nima Sanadgol, Fereshteh Golab, Majid Katebi, Amir Hossein Abdolghaffari, Mohammad Hosein Farzaei, Mohammad Abdollahi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-04-01
Subjects:	ubiquitin-proteasome pathway neurodegenerative diseases Alzheimer's disease Parkinson's disease Huntington disease Amyotrophic lateral sclerosis
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2020.00361/full

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