The role of synaptic protein NSF in the development and progression of neurological diseases
This document provides a comprehensive examination of the pivotal function of the N-ethylmaleimide-sensitive factor (NSF) protein in synaptic function. The NSF protein directly participates in critical biological processes, including the cyclic movement of synaptic vesicles (SVs) between exocytosis...
| Published in: | Frontiers in Neuroscience |
|---|---|
| Main Authors: | Jingyue Yang, Lingyue Kong, Li Zou, Yumin Liu |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-10-01
|
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2024.1395294/full |
Similar Items
Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes
by: Eric A Prinslow, et al.
Published: (2017-09-01)
by: Eric A Prinslow, et al.
Published: (2017-09-01)
PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly
by: Jeff Coleman, et al.
Published: (2018-01-01)
by: Jeff Coleman, et al.
Published: (2018-01-01)
Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles
by: Jeremy Leitz, et al.
Published: (2014-11-01)
by: Jeremy Leitz, et al.
Published: (2014-11-01)
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
by: Josep Rizo, et al.
Published: (2025-05-01)
by: Josep Rizo, et al.
Published: (2025-05-01)
NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin
by: Ucheor B Choi, et al.
Published: (2018-07-01)
by: Ucheor B Choi, et al.
Published: (2018-07-01)
The role of RIM in neurotransmitter release: promotion of synaptic vesicle docking, priming, and fusion
by: Shanshan Wu, et al.
Published: (2023-04-01)
by: Shanshan Wu, et al.
Published: (2023-04-01)
A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion
by: Zhuo Guan, et al.
Published: (2017-09-01)
by: Zhuo Guan, et al.
Published: (2017-09-01)
Synaptic vesicle proteins and active zone plasticity
by: Robert J Kittel, et al.
Published: (2016-04-01)
by: Robert J Kittel, et al.
Published: (2016-04-01)
Alpha-Synuclein and Calpains Disrupt SNARE-Mediated Synaptic Vesicle Fusion During Manganese Exposure in SH-SY5Y Cells
by: Can Wang, et al.
Published: (2018-12-01)
by: Can Wang, et al.
Published: (2018-12-01)
Synapsins and the Synaptic Vesicle Reserve Pool: Floats or Anchors?
by: Minchuan Zhang, et al.
Published: (2021-03-01)
by: Minchuan Zhang, et al.
Published: (2021-03-01)
Neuronal SNARE complex assembly guided by Munc18‐1 and Munc13‐1
by: Shen Wang, et al.
Published: (2022-11-01)
by: Shen Wang, et al.
Published: (2022-11-01)
Multiple paralogues of α-SNAP in Giardia lamblia exhibit independent subcellular localization and redistribution during encystation and stress
by: Shankari Prasad Datta, et al.
Published: (2018-10-01)
by: Shankari Prasad Datta, et al.
Published: (2018-10-01)
An evaluation of properly operated NSF/ANSI-53 Pb certified drinking water filters in Benton Harbor, MI
by: Jennifer Tully, et al.
Published: (2024-02-01)
by: Jennifer Tully, et al.
Published: (2024-02-01)
A mechanism for exocytotic arrest by the Complexin C-terminus
by: Mazen Makke, et al.
Published: (2018-07-01)
by: Mazen Makke, et al.
Published: (2018-07-01)
Downregulation of Ripk1 and Nsf mediated by CRISPR-CasRx ameliorates stroke volume and neurological deficits after ischemia stroke in mice
by: Xincheng Song, et al.
Published: (2024-06-01)
by: Xincheng Song, et al.
Published: (2024-06-01)
Accessory and Central α-helices of Complexin Selectively Activate Ca2+ Triggering of Synaptic Exocytosis
by: Yi Yu, et al.
Published: (2018-02-01)
by: Yi Yu, et al.
Published: (2018-02-01)
APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses
by: Tomas Fanutza, et al.
Published: (2015-11-01)
by: Tomas Fanutza, et al.
Published: (2015-11-01)
Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiology
by: Xiling Bian, et al.
Published: (2023-12-01)
by: Xiling Bian, et al.
Published: (2023-12-01)
A Stimulation Function of Synaptotagmin-1 in Ternary SNARE Complex Formation Dependent on Munc18 and Munc13
by: Yun Li, et al.
Published: (2017-08-01)
by: Yun Li, et al.
Published: (2017-08-01)
SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions
by: Anna Kádková, et al.
Published: (2024-02-01)
by: Anna Kádková, et al.
Published: (2024-02-01)
Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner
by: Zhuo Guan, et al.
Published: (2020-04-01)
by: Zhuo Guan, et al.
Published: (2020-04-01)
Synaptic Vesicle Glycoprotein 2C: a role in Parkinson’s disease
by: Chu Hua Chang, et al.
Published: (2024-09-01)
by: Chu Hua Chang, et al.
Published: (2024-09-01)
Penentuan Indeks Kualitas Air Sungai Bedadung Kabupaten Jember Menggunakan Metode IP dan NSF-WQI
by: Elida Novita, et al.
Published: (2023-05-01)
by: Elida Novita, et al.
Published: (2023-05-01)
Recommended Practices for Integrating Education, Diversity, and Research: Five Lessons Learned from NSF Science and Technology Centers
by: Barbara C. Bruno, et al.
Published: (2014-04-01)
by: Barbara C. Bruno, et al.
Published: (2014-04-01)
Water quality status in different aquatic environments in Thi- Qar province based on NSF-WQI
by: Afaq T. Farhood
Published: (2019-04-01)
by: Afaq T. Farhood
Published: (2019-04-01)
Water quality status in different aquatic environments in Thi- Qar province based on NSF-WQI
by: Afaq T. Farhood
Published: (2019-04-01)
by: Afaq T. Farhood
Published: (2019-04-01)
Water quality status in different aquatic environments in Thi- Qar province based on NSF-WQI
by: Afaq T. Farhood
Published: (2019-04-01)
by: Afaq T. Farhood
Published: (2019-04-01)
Examining the Water Quality Situation in Klampok River, Semarang through the Application of the NSF-WQI (National Sanitation Foundation – Water Quality Index) Model
by: Syafrudin Syafrudin, et al.
Published: (2023-07-01)
by: Syafrudin Syafrudin, et al.
Published: (2023-07-01)
Analisis Kualitas Air Daerah Irigasi Pendil dan Watupala Desa Kutaliman, Banyumas, Jawa Tengah Menggunakan Metode STORET dan NSF-WQI
by: Sesilia Rani Samudra, et al.
Published: (2024-08-01)
by: Sesilia Rani Samudra, et al.
Published: (2024-08-01)
Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex
by: Ucheor B Choi, et al.
Published: (2016-06-01)
by: Ucheor B Choi, et al.
Published: (2016-06-01)
Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity
by: Frédéric Doussau, et al.
Published: (2017-10-01)
by: Frédéric Doussau, et al.
Published: (2017-10-01)
A theory of synaptic transmission
by: Bin Wang, et al.
Published: (2021-12-01)
by: Bin Wang, et al.
Published: (2021-12-01)
Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice
by: Tuhin Virmani, et al.
Published: (2005-11-01)
by: Tuhin Virmani, et al.
Published: (2005-11-01)
Membrane bridging by Munc13-1 is crucial for neurotransmitter release
by: Bradley Quade, et al.
Published: (2019-02-01)
by: Bradley Quade, et al.
Published: (2019-02-01)
Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming
by: Bassam Tawfik, et al.
Published: (2021-03-01)
by: Bassam Tawfik, et al.
Published: (2021-03-01)
The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A
by: Andrea Salazar Lázaro, et al.
Published: (2024-03-01)
by: Andrea Salazar Lázaro, et al.
Published: (2024-03-01)
Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses
by: Dario Maschi, et al.
Published: (2020-02-01)
by: Dario Maschi, et al.
Published: (2020-02-01)
The accessory helix of complexin functions by stabilizing central helix secondary structure
by: Daniel T Radoff, et al.
Published: (2014-11-01)
by: Daniel T Radoff, et al.
Published: (2014-11-01)
Altered synaptic homeostasis: a key factor in the pathophysiology of depression
by: Bokai Wang, et al.
Published: (2025-02-01)
by: Bokai Wang, et al.
Published: (2025-02-01)
APOE4 triggers dysregulated synaptic vesicle release by disrupting SNARE complex assembly
by: Feng Chen, et al.
Published: (2025-06-01)
by: Feng Chen, et al.
Published: (2025-06-01)
Similar Items
-
Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes
by: Eric A Prinslow, et al.
Published: (2017-09-01) -
PRRT2 Regulates Synaptic Fusion by Directly Modulating SNARE Complex Assembly
by: Jeff Coleman, et al.
Published: (2018-01-01) -
Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles
by: Jeremy Leitz, et al.
Published: (2014-11-01) -
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
by: Josep Rizo, et al.
Published: (2025-05-01) -
NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin
by: Ucheor B Choi, et al.
Published: (2018-07-01)
