Detection capacity of small intestine bacterial or methanogen overgrowth by lactose and fructose breath testing in the adult population

• الحاوية / القاعدة: Advances in Laboratory Medicine
• المؤلفون الرئيسيون: Laserna Mendieta Emilio José, Martín Dominguez Verónica, Pérez Lucendo Irene, Granero Cremades Inmaculada, Ferreirós Martínez Raquel, Álvarez Malé Tomás, Sanz De Benito María Ángeles, Santander Cecilio
• التنسيق: مقال
• اللغة: الإنجليزية
• منشور في: De Gruyter 2024-08-01
• الموضوعات: fructose malabsorption/intolerance; lactose malabsorption/intolerance; small intestine bacterial overgrowth; intestinal methanogenic overgrowth; exhaled breath test
• الوصول للمادة أونلاين: https://doi.org/10.1515/almed-2024-0115
• تدمد: 2628-491X

Exhaled breath tests (BTs) are the main diagnostic method for fructose and lactose malabsorption/intolerance (FI and LI, respectively) and for detecting small intestine bacterial or methanogen overgrowth (SIBO/IMO). Although FI/LI-BTs may provide evidence of the presence of SIBO/IMO, there is limited literature evaluating their reliability for this purpose. The objective of this study was to assess the sensitivity and specificity of FI/LI-BTs in detecting SIBO and their concordance with SIBO-BTs in the identification of IMO.