Over-expression of miR-217 regulates EZH2 to promote osteogenic differentiation of BM-MSCs in osteoporotic mouse models

Objective To explore the effect of microRNA-217 (miR-217) on the osteogenic differentiation of bone marrow mesenchymal stem cells (BM-MSCs) in osteoporosis (OP) mouse model and potential regulatory mechanism. Methods The mice were divided into OP group and sham operation (sham) group with 12 in each...

Full description

Bibliographic Details

Published in:	Jichu yixue yu linchuang
Main Author:	RUAN Feng, LI He-wei, GONG Yan-lin, LIU Jia-li, LIU Ping
Format:	Article
Language:	Chinese
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-09-01
Subjects:	microrna-217| enhancer of zeste homolog 2(ezh2)| bone marrow derived mesenchymal stem cell(bm-msc)| osteoporosis
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-42-9-1406.pdf