Somatic Mutations and Autoimmunity

Autoimmune diseases are among the most common chronic illness caused by a dysregulated immune response against self-antigens. Close to 5% of the general population in Western countries develops some form of autoimmunity, yet its underlying causes, although intensively studied, are still not fully kn...

Full description

Bibliographic Details
Published in:	Cells
Main Authors:	Maha Alriyami, Constantin Polychronakos
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Subjects:	somatic mutations autoimmunity lymphocytes
Online Access:	https://www.mdpi.com/2073-4409/10/8/2056

Similar Items

Somatic evolutionary timings of driver mutations
by: Karen Gomez, et al.
Published: (2018-01-01)

Next Generation Sequencing for Detecting Somatic FAS Mutations in Patients With Autoimmune Lymphoproliferative Syndrome
by: Marta López-Nevado, et al.
Published: (2021-04-01)

Somatic mutations substantially increase the per‐generation mutation rate in the conifer Picea sitchensis
by: Vincent C. T. Hanlon, et al.
Published: (2019-08-01)

Possible relationship between the somatic mutations and the formation of cancers
by: Cao Yixuan
Published: (2022-01-01)

Somatic BRCA Mutation in High Grade Epithelial Ovarian Cancer Patients
by: Tarinee Manchana, et al.
Published: (2019-01-01)

Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
by: Jüri Reimand, et al.
Published: (2013-01-01)

Somatic mutations in colorectal cancer: regional experience
by: Nikolai A. Ognerubov, et al.
Published: (2022-07-01)

Age-related somatic mutation burden in human tissues
by: Peijun Ren, et al.
Published: (2022-09-01)

A simple approach for classifying new mutations as somatic or germinal in DNA samples lacking paired tissue
by: Ignacio Erquiaga, et al.
Published: (2014-06-01)

Brain somatic mutations in Alzheimer’s disease: linking genetic mosaicism to neurodegeneration
by: Zuguang Li, et al.
Published: (2025-10-01)

Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data
by: Alexandre Coudray, et al.
Published: (2018-07-01)

Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals
by: Yaroslav Kainov, et al.
Published: (2024-12-01)

Somatic mutation rates scale with time not growth rate in long-lived tropical trees
by: Akiko Satake, et al.
Published: (2024-10-01)

Somatic Mutations Detected in Parkinson Disease Could Affect Genes With a Role in Synaptic and Neuronal Processes
by: Irene Lobon, et al.
Published: (2022-04-01)

Editorial: Somatic mutations, genome mosaicism and aging
by: Michael A. Lodato, et al.
Published: (2023-01-01)

Somatic Mutation Accumulations in Micropropagated Cannabis Are Proportional to the Number of Subcultures
by: Kristian Adamek, et al.
Published: (2024-07-01)

Increase of somatic cell mutations in oxidative damage-sensitive drosophila
by: Ryota Koike, et al.
Published: (2018-01-01)

Germline PALB2 Mutations in Cancers and Its Distinction From Somatic PALB2 Mutations in Breast Cancers
by: Zhe-Yu Hu, et al.
Published: (2020-08-01)

Research Progress of Prostate Cancer Somatic Mutation and Treatment
by: WU Liyi, et al.
Published: (2023-07-01)

Clinical Significance of Pathogenicity of Somatic Mutations in Oral Leukoplakia: a Prospective Observational Study
by: N. A. Karpuk, et al.
Published: (2023-08-01)

Precise Identification of Recurrent Somatic Mutations in Oral Cancer Through Whole-Exome Sequencing Using Multiple Mutation Calling Pipelines
by: Li-Han Lin, et al.
Published: (2021-11-01)

mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls
by: Wenjie Guo, et al.
Published: (2023-05-01)

Human aging and somatic point mutations in mtDNA: a comparative study of generational differences (grandparents and grandchildren)
by: Anderson Nonato do Rosário Marinho, et al.
Published: (2011-01-01)

Somatic genomic variants in refractory cytopenia of childhood
by: Diego F. Coutinho, et al.
Published: (2021-09-01)

Characterization of Three Somatic Mutations in the 3′UTR of <i>RRAS2</i> and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia
by: Marta Lacuna, et al.
Published: (2023-11-01)

Somatic Mutations in Surgically Treated Colorectal Liver Metastases: An Overview
by: Jane Wang, et al.
Published: (2024-04-01)

Comparison of Germline versus Somatic BAP1 Mutations for Risk of Metastasis in Uveal Melanoma
by: K. G. Ewens, et al.
Published: (2018-11-01)

The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
by: Monica Sanchez-Contreras, et al.
Published: (2023-02-01)

Comprehensive genomic profiling of Chinese lung cancer characterizes germline-somatic mutation interactions influencing cancer risk
by: Ning Zhou, et al.
Published: (2025-02-01)

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing
by: Nan Lyu, et al.
Published: (2016-01-01)

The Role of Somatic Mutations in Ischemic Stroke: CHIP’s Impact on Vascular Health
by: Aiman Kinzhebay, et al.
Published: (2025-01-01)

Somatic mutation spectrum of a Chinese cohort of pediatrics with vascular malformations
by: Bin Zhang, et al.
Published: (2023-09-01)

Evaluating somatic tumor mutation detection without matched normal samples
by: Jamie K. Teer, et al.
Published: (2017-09-01)

Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (<i>PRNP</i>) in Cancer Patients
by: Yong-Chan Kim, et al.
Published: (2020-06-01)

Multigene Panel Sequencing Reveals Cancer-Specific and Common Somatic Mutations in Colorectal Cancer Patients: An Egyptian Experience
by: Amira Salah El-Din Youssef, et al.
Published: (2022-03-01)

Somatic variants of potential clinical significance in the tumors of BRCA phenocopies
by: Lela Buckingham, et al.
Published: (2019-07-01)

The NF1 somatic mutational landscape in sporadic human cancers
by: Charlotte Philpott, et al.
Published: (2017-06-01)

Different NGS identification methods of somatic mutation sites in solid tumors impact TMB results
by: Xueshu Chen, et al.
Published: (2025-03-01)

Methods for the detection of tumor-specific single nucleotide somatic mutations in plasma cDNA samples
by: L. M. Dyakov, et al.
Published: (2022-10-01)

Investigation of Somatic Mutations in Human Brains Targeting Genes Associated With Parkinson's Disease
by: Melissa Leija-Salazar, et al.
Published: (2020-10-01)