Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway

BackgroundWhile platelet hyperreactivity constitutes an independent risk factor for major adverse cardiovascular events (MACEs) in coronary artery disease, its molecular underpinnings remain poorly characterized. Recent advances in transcriptomic profiling have revealed potential associations with s...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shengnan Shi, Jiaming Gao, Yehao Zhang, Min Zhan, Zhanfei Tan, Peili Wang, Jianhua Fu, Jianxun Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	coronary heart disease platelet hyperreactivity Talin-1 and αIIbβ3-mediated bidirectional signaling pathway platelet transcriptome interleukin
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1535182/full