Characteristics of clinical manifestations of gout in the elderly people

Introduction. Gout in elderly patients is characterized a pronounced comorbid background [2,8-10], which causes difficulties in their management [9]. Objectives of the study. Analysis of the comorbid background for gout in different age groups. Identification of risk factors characteristics, the on...

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Published in:Romanian Journal of Rheumatology
Main Authors: Larisa Rotaru, Liliana Groppa, Catalin Codreanu, Larisa Spinei, Oleg Arnaut, Eugeniu Russu, Alesea Nistor, Lucia Dutca, Cristina Pamfil, Cornelia Cornea
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2022-09-01
Subjects:
Online Access:https://rjr.com.ro/articles/2022.3/RJR_2022_3_Art-03.pdf
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author Larisa Rotaru
Liliana Groppa
Catalin Codreanu
Larisa Spinei
Oleg Arnaut
Eugeniu Russu
Alesea Nistor
Lucia Dutca
Cristina Pamfil
Cornelia Cornea
author_facet Larisa Rotaru
Liliana Groppa
Catalin Codreanu
Larisa Spinei
Oleg Arnaut
Eugeniu Russu
Alesea Nistor
Lucia Dutca
Cristina Pamfil
Cornelia Cornea
author_sort Larisa Rotaru
collection DOAJ
container_title Romanian Journal of Rheumatology
description Introduction. Gout in elderly patients is characterized a pronounced comorbid background [2,8-10], which causes difficulties in their management [9]. Objectives of the study. Analysis of the comorbid background for gout in different age groups. Identification of risk factors characteristics, the onset and evolution of gout in elderly people compared to middle-aged patients. Material and methods. To achieve the goal of the cross-sectional study, 237 patients with gout (average age for the men 60±8.0 years and for the women 63±9.0 years) were examined. Results. The patients were separated into two groups, depending on the age of onset of gout: the age of onset up to and including 59 years (group I, 146 people) and the age of onset after 60 years inclusive (group II, 91 people). The average age in group I was 58.1±11.7 years, in group II - 72.8±4.1 years (p<0,1). Conclusions. The average number of concomitant diseases is 2 times higher in the group of gout patients aged 60 years and older (4.0 [3.0; 5.0]) than in the group of patients with gout under the age of 59 years inclusive (2.0 [2.0;3.0], p <0,1), in patients with the onset of gout at the age of 59 years inclusive, the development of coronary artery disease, chronic heart failure and nephrolithiasis occurs significantly earlier than in patients with the onset of gout at the age of 60 years and older (48,4±6,9 years and 59,1±5,0 years; 53,6 ± 3,4 years and 65,6±9,0 years; 37,3±8,9 years and, respectively, 54,9±14,6 years, p<0,05 in all cases).
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spelling doaj-art-eef75ffca6ad4c938b5f6e8a02795aa92025-08-19T20:14:14ZengAmaltea Medical Publishing HouseRomanian Journal of Rheumatology1843-07912069-60862022-09-0131311812310.37897/RJR.2022.3.3Characteristics of clinical manifestations of gout in the elderly peopleLarisa Rotaru0Liliana Groppa1Catalin Codreanu2Larisa Spinei3Oleg Arnaut4Eugeniu Russu5Alesea Nistor6Lucia Dutca7Cristina Pamfil8Cornelia Cornea9“Timofei Mosneaga“ Republican Clinical Hospital, Rheumatology Laboratory, Chisinau, Republic of Moldova; Department of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of Moldova “Timofei Mosneaga“ Republican Clinical Hospital, Rheumatology Laboratory, Chisinau, Republic of Moldova; Department of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of Moldova Department 5 Internal Medicine (Cardiology, Gastroenterology, Hepatology, Rheumatology, Geriatrics), Family Medicine, Occupational Medicine Faculty, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Social Medicine and Management, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaInformation Laboratory, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaDepartment of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaDepartment of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaDepartment of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaRheumatology Department, ”Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Internal Medicine, Rheumatology and Nephrology Discipline, ”Nicolae Testemitanu” State University of Medicine and Pharmacy, Chisinau, Republic of MoldovaIntroduction. Gout in elderly patients is characterized a pronounced comorbid background [2,8-10], which causes difficulties in their management [9]. Objectives of the study. Analysis of the comorbid background for gout in different age groups. Identification of risk factors characteristics, the onset and evolution of gout in elderly people compared to middle-aged patients. Material and methods. To achieve the goal of the cross-sectional study, 237 patients with gout (average age for the men 60±8.0 years and for the women 63±9.0 years) were examined. Results. The patients were separated into two groups, depending on the age of onset of gout: the age of onset up to and including 59 years (group I, 146 people) and the age of onset after 60 years inclusive (group II, 91 people). The average age in group I was 58.1±11.7 years, in group II - 72.8±4.1 years (p<0,1). Conclusions. The average number of concomitant diseases is 2 times higher in the group of gout patients aged 60 years and older (4.0 [3.0; 5.0]) than in the group of patients with gout under the age of 59 years inclusive (2.0 [2.0;3.0], p <0,1), in patients with the onset of gout at the age of 59 years inclusive, the development of coronary artery disease, chronic heart failure and nephrolithiasis occurs significantly earlier than in patients with the onset of gout at the age of 60 years and older (48,4±6,9 years and 59,1±5,0 years; 53,6 ± 3,4 years and 65,6±9,0 years; 37,3±8,9 years and, respectively, 54,9±14,6 years, p<0,05 in all cases).https://rjr.com.ro/articles/2022.3/RJR_2022_3_Art-03.pdfgoutelderlycomorbidities
spellingShingle Larisa Rotaru
Liliana Groppa
Catalin Codreanu
Larisa Spinei
Oleg Arnaut
Eugeniu Russu
Alesea Nistor
Lucia Dutca
Cristina Pamfil
Cornelia Cornea
Characteristics of clinical manifestations of gout in the elderly people
gout
elderly
comorbidities
title Characteristics of clinical manifestations of gout in the elderly people
title_full Characteristics of clinical manifestations of gout in the elderly people
title_fullStr Characteristics of clinical manifestations of gout in the elderly people
title_full_unstemmed Characteristics of clinical manifestations of gout in the elderly people
title_short Characteristics of clinical manifestations of gout in the elderly people
title_sort characteristics of clinical manifestations of gout in the elderly people
topic gout
elderly
comorbidities
url https://rjr.com.ro/articles/2022.3/RJR_2022_3_Art-03.pdf
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