Thermodynamic Model for B-Z Transition of DNA Induced by Z-DNA Binding Proteins

Z-DNA is stabilized by various Z-DNA binding proteins (ZBPs) that play important roles in RNA editing, innate immune response, and viral infection. In this review, the structural and dynamics of various ZBPs complexed with Z-DNA are summarized to better understand the mechanisms by which ZBPs select...

Full description

Bibliographic Details
Published in:	Molecules
Main Authors:	Ae-Ree Lee, Na-Hyun Kim, Yeo-Jin Seo, Seo-Ree Choi, Joon-Hwa Lee
Format:	Article
Language:	English
Published:	MDPI AG 2018-10-01
Subjects:	Z-DNA DNA-protein interaction B-Z transition Z-DNA binding protein
Online Access:	https://www.mdpi.com/1420-3049/23/11/2748

Similar Items

Comparative review on left-handed Z-DNA
by: Reetabrita Roy, et al.
Published: (2021-04-01)

Assessing B-Z DNA Transitions in Solutions via Infrared Spectroscopy
by: Mengmeng Duan, et al.
Published: (2023-06-01)

Construction of ssDNA-Attached LR-Chimera Involving Z-DNA for ZBP1 Binding Analysis
by: Lin Li, et al.
Published: (2022-06-01)

Structure and Formation of Z-DNA and Z-RNA
by: Jeffrey B. Krall, et al.
Published: (2023-01-01)

Emapunil attenuates ulcerative colitis by suppressing Z-DNA binding protein 1 driven pyroptosis and pro-inflammatory polarization in macrophages
by: Shenghao Xv, et al.
Published: (2026-05-01)

The ancient Z-DNA and Z-RNA specific Zα fold has evolved modern roles in immunity and transcription through the natural selection of flipons
by: Alan Herbert
Published: (2024-06-01)

Z-DNA-Binding Protein 1 Is Critical for Controlling Virus Replication and Survival in West Nile Virus Encephalitis
by: Hussin A. Rothan, et al.
Published: (2019-09-01)

The evolutionary entanglement of flipons with zinc fingers and retroelements has engendered a large family of Z-DNA and G-quadruplex binding proteins
by: Alan Herbert
Published: (2025-10-01)

Behavior of B- and Z-DNA Crystals under High Hydrostatic Pressure
by: Thierry Prangé, et al.
Published: (2022-06-01)

Environmental high temperature induced cartilage damage through triggering programmed necrosis mediated by producing left-handed DNA
by: Sun Yingfei, et al.
Published: (2025-02-01)

Enrichment of Z-DNA-Forming Sequences Within Super-Enhancers: A Computational and Population-Based Study
by: Yulia V. Makus, et al.
Published: (2025-05-01)

Highly alkali-resistant Enterococcus faecalis induces compromised PANoptosis of macrophage via ZBP1
by: XIAO Yifang, LIU Runze, OU Dongchen, FAN Wei
Published: (2026-04-01)

Dissecting non-B DNA structural motifs in untranslated regions of eukaryotic genomes
by: Aruna Sesha Chandrika Gummadi, et al.
Published: (2024-11-01)

High-throughput characterization of the role of non-B DNA motifs on promoter function
by: Ilias Georgakopoulos-Soares, et al.
Published: (2022-04-01)

Reissner-Mindlin板的Z-Z矩形元的改进
by: 胡兵, et al.
Published: (2010-01-01)

The human PTGR1 gene expression is controlled by TE-derived Z-DNA forming sequence cooperating with miR-6867-5p
by: Du Hyeong Lee, et al.
Published: (2024-02-01)

DNA-binding proteins essential for protein-primed bacteriophage ø29 DNA replication
by: Margarita Salas, et al.
Published: (2016-08-01)

DNA replication initiation timing is important for maintaining genome integrity
by: Tristan T. Reed, et al.
Published: (2025-08-01)

ALU non-B-DNA conformations, flipons, binary codes and evolution
by: Alan Herbert
Published: (2020-06-01)

Expression of anti-Z-DNA single chain antibody variable fragment on the filamentous phage surface
by: A.Q. Maranhão, et al.
Published: (2000-05-01)

Noble Metal Complexes and Non-Canonical Nucleic Acids: From G-Quadruplex Recognition to Emerging Functional Architectures
by: Damiano Cirri, et al.
Published: (2026-06-01)

The possible relationship between epistaxis and protein Z plasma levels
by: Turan Turhan, et al.
Published: (2017-12-01)

Structural profile of ligand-based inhibition of bacterial FtsZ
by: D. S. Ozheriedov, et al.
Published: (2023-09-01)

Chlorogenic Acid Ameliorates CVB3-Induced Viral Myocarditis by Suppressing Viral Replication and ZBP1-Mediated PANoptosis
by: Junbo Huang, et al.
Published: (2026-06-01)

PKZ, a Fish-Unique eIF2α Kinase Involved in Innate Immune Response
by: Chuxin Wu, et al.
Published: (2020-03-01)

On Z*-open, Z*-closed functions
by: MOHAMMAD AL-JUHANI, et al.
Published: (2014-09-01)

Zinc fingers: DNA binding and protein-protein interactions
by: OSCAR LEON, et al.
Published: (2000-01-01)

A precise solution to the shortest path optimization problem in graphs using Z-numbers
by: Nurdoğan Güner, et al.
Published: (2024-10-01)

Single-Stranded DNA Binding Proteins and Their Identification Using Machine Learning-Based Approaches
by: Jun-Tao Guo, et al.
Published: (2022-08-01)

Blood Plasma Exosomes Contain Circulating DNA in Their Crown
by: Oleg Tutanov, et al.
Published: (2022-03-01)

Analysis and prediction of single-stranded and double-stranded DNA binding proteins based on protein sequences
by: Wei Wang, et al.
Published: (2017-06-01)

zLinux: Access Control inside Mainframes
by: Andrey Michaylovich Kanner
Published: (2014-12-01)

A Novel Z-Ring Associated Protein ZapA-Like Protein (PA5407) From Pseudomonas aeruginosa Promotes FtsZ to Form Double Filaments
by: Xiaoyu Wang, et al.
Published: (2021-08-01)

The Simple Biology of Flipons and Condensates Enhances the Evolution of Complexity
by: Alan Herbert
Published: (2021-08-01)

Formulaic Prediction of Z-Plasty Outcomes Relative to Z Scar Lengthening, Z Flap Tension, and Area of Distortion, and Determination of the Multiple Z-Plasty Configurations that Optimally Increase Z Scar Length, Decrease Z Flap Tension, and Decrease Area of Distortion
by: Nutthawut Akaranuchat, et al.
Published: (2019-11-01)

ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway
by: Shengguang Yan, et al.
Published: (2024-07-01)

African swine fever virus early protein pI73R suppresses the type-I IFN promoter activities
by: Danh Cong Lai, et al.
Published: (2024-05-01)

Mountain pass solution for the weighted Dirichlet ( p ( z ) , q ( z ) ) $(p(z),q(z))$ -problem
by: Nadiyah Hussain Alharthi, et al.
Published: (2022-06-01)

Application of the Z-Information-Based Scenarios for Energy Transition Policy Development
by: Mahammad Nuriyev, et al.
Published: (2025-03-01)

Structure–Function Analysis of RBP7910: An Editosome Z-Binding Protein in Trypanosomatids
by: Curtis Ehlert, et al.
Published: (2023-10-01)