Use of etiotropic and pathogenetic medicines for COVID-19 in patients with renal failure and/or on dialysis

Impaired kidney function may influence pharmacokinetics of most of the drugs, including the ones used in COVID-19. In this publication, the most important pharmacokinetic parameters and dose adjustment approaches are provided, based on The Renal Drug Handbook и Sanford Guide. In the majority of case...

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Bibliographic Details
Published in:Качественная клиническая практика
Main Authors: V. M. Tsvetov, I. N. Sychev, D. A. Sychev
Format: Article
Language:Russian
Published: Izdatelstvo OKI 2020-10-01
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Online Access:https://www.clinvest.ru/jour/article/view/524
Description
Summary:Impaired kidney function may influence pharmacokinetics of most of the drugs, including the ones used in COVID-19. In this publication, the most important pharmacokinetic parameters and dose adjustment approaches are provided, based on The Renal Drug Handbook и Sanford Guide. In the majority of cases, mild kidney function reduction does not necessitate dose adjustment. Each case should be considered individually, measuring benefits against risks.
ISSN:2588-0519
2618-8473