Nanotechnology-driven nanoemulsion gel for enhanced transdermal delivery of Sophora alopecuroides L. empyreumatic oil: formulation optimization, and anti-biofilm efficacy

Sophora alopecuroides L. empyreumatic oil (SoA oil) exhibits therapeutic potential for psoriasis and eczema but suffers from poor skin permeability and formulation challenges. To overcome these limitations, a nanoemulsion (NE) gel was developed. The NE was optimized using pseudo-ternary phase diagra...

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Bibliographic Details
Published in:Frontiers in Bioengineering and Biotechnology
Main Authors: Xiuli Cheng, Xiangyu Zhou, Wenping Wang, Jing Chen, Yikun Cao, Jia Wen, Jin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Subjects:
Sophora alopecuroide L.
empyreumatic oil
nanoemulsion gel
skin permeation
irritation
anti-biofilm
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1586924/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1586924/full

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