Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age

Summary: Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early post-natal/juvenile (<2 m.o.) Tam induction, but age-related neurodegeneration and aging studies can require Cre induction in older mice (>...

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Bibliographic Details

Published in:	iScience
Main Authors:	Collyn M. Kellogg, Kevin Pham, Sunghwan Ko, Jillian E.J. Cox, Adeline H. Machalinski, Michael B. Stout, Amanda L. Sharpe, Michael J. Beckstead, Ana J. Chucair-Elliott, Sarah R. Ocañas, Willard M. Freeman
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	Natural sciences Biological sciences Genomics Biological sciences research methodologies Biology experimental methods
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223024902