Molecular basis of antibiotic self-resistance in a bee larvae pathogen
The authors show that the N-acetyltransferase PamZ acts as a self-resistance factor disabling the antibacterial paenilamicin that is produced by the honey bee larvae pathogen Paenibacillus larvae.
| الحاوية / القاعدة: | Nature Communications |
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| المؤلفون الرئيسيون: | , , , , , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Nature Portfolio
2022-04-01
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| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41467-022-29829-w |
| _version_ | 1851886724884463616 |
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| author | Tam Dang Bernhard Loll Sebastian Müller Ranko Skobalj Julia Ebeling Timur Bulatov Sebastian Gensel Josefine Göbel Markus C. Wahl Elke Genersch Andi Mainz Roderich D. Süssmuth |
| author_facet | Tam Dang Bernhard Loll Sebastian Müller Ranko Skobalj Julia Ebeling Timur Bulatov Sebastian Gensel Josefine Göbel Markus C. Wahl Elke Genersch Andi Mainz Roderich D. Süssmuth |
| author_sort | Tam Dang |
| collection | DOAJ |
| container_title | Nature Communications |
| description | The authors show that the N-acetyltransferase PamZ acts as a self-resistance factor disabling the antibacterial paenilamicin that is produced by the honey bee larvae pathogen Paenibacillus larvae. |
| format | Article |
| id | doaj-art-efd0e34fbaa048d5bbc9b3660ecfcfae |
| institution | Directory of Open Access Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| spelling | doaj-art-efd0e34fbaa048d5bbc9b3660ecfcfae2025-08-19T22:11:15ZengNature PortfolioNature Communications2041-17232022-04-0113111110.1038/s41467-022-29829-wMolecular basis of antibiotic self-resistance in a bee larvae pathogenTam Dang0Bernhard Loll1Sebastian Müller2Ranko Skobalj3Julia Ebeling4Timur Bulatov5Sebastian Gensel6Josefine Göbel7Markus C. Wahl8Elke Genersch9Andi Mainz10Roderich D. Süssmuth11Institut für Chemie, Technische Universität BerlinInstitut für Chemie und Biochemie, Strukturbiochemie, Freie Universität BerlinInstitut für Chemie, Technische Universität BerlinInstitut für Chemie, Technische Universität BerlinInstitute for Bee Research, Department of Molecular Microbiology and Bee DiseasesInstitut für Chemie, Technische Universität BerlinInstitut für Chemie, Technische Universität BerlinInstitute for Bee Research, Department of Molecular Microbiology and Bee DiseasesInstitut für Chemie und Biochemie, Strukturbiochemie, Freie Universität BerlinInstitute for Bee Research, Department of Molecular Microbiology and Bee DiseasesInstitut für Chemie, Technische Universität BerlinInstitut für Chemie, Technische Universität BerlinThe authors show that the N-acetyltransferase PamZ acts as a self-resistance factor disabling the antibacterial paenilamicin that is produced by the honey bee larvae pathogen Paenibacillus larvae.https://doi.org/10.1038/s41467-022-29829-w |
| spellingShingle | Tam Dang Bernhard Loll Sebastian Müller Ranko Skobalj Julia Ebeling Timur Bulatov Sebastian Gensel Josefine Göbel Markus C. Wahl Elke Genersch Andi Mainz Roderich D. Süssmuth Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title | Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title_full | Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title_fullStr | Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title_full_unstemmed | Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title_short | Molecular basis of antibiotic self-resistance in a bee larvae pathogen |
| title_sort | molecular basis of antibiotic self resistance in a bee larvae pathogen |
| url | https://doi.org/10.1038/s41467-022-29829-w |
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