Co‐occurring KEAP1 and TP53 mutations in lung squamous cell carcinoma induced primary resistance to thoracic radiotherapy: A case report

Abstract In lung squamous cell carcinoma, KEAP1 mutations frequently coexist with TP53 mutations. A preclinical model showed that mutations leading to the activation of the KEAP1–NRF2 pathway contribute to clinical radioresistance. However, there have been few clinical reports on the association bet...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Thoracic Cancer
المؤلفون الرئيسيون: Rumi Nishimura, Tatsuya Yoshida, Masahiro Torasawa, Tairo Kashihara, Yuichiro Ohe
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2023-01-01
الموضوعات:
KEAP
lung squamous cell carcinoma
next‐generation sequencing
thoracic radiotherapy
TP53
الوصول للمادة أونلاين:https://doi.org/10.1111/1759-7714.14751

الانترنت

https://doi.org/10.1111/1759-7714.14751

مواد مشابهة