Central retinal vein occlusion associated with Bartonella henselae infection
Abstract Purpose To report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection. Observation A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms bu...
| الحاوية / القاعدة: | Journal of Ophthalmic Inflammation and Infection |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
SpringerOpen
2023-03-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s12348-023-00334-5 |
| _version_ | 1850143859384778752 |
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| author | Sunil Bellur Amir Ali Nam V. Nguyen Joshua K. Fernandes Shilpa Kodati |
| author_facet | Sunil Bellur Amir Ali Nam V. Nguyen Joshua K. Fernandes Shilpa Kodati |
| author_sort | Sunil Bellur |
| collection | DOAJ |
| container_title | Journal of Ophthalmic Inflammation and Infection |
| description | Abstract Purpose To report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection. Observation A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms but reported prior exposure to fleas. Best corrected visual acuity (BCVA) was 20/400 in the left eye. Clinical examination revealed a CRVO with atypical features including significant peripapillary exudates and peripheral vascular sheathing. Laboratory testing revealed elevated B. henselae IgG titers (1:512) with no abnormalities on hypercoagulability testing. The patient was treated with doxycycline and aflibercept with an excellent clinical response and improvement in BCVA to 20/25 in the left eye two months later. Conclusion CRVO is a rare but sight-threatening complication of ocular bartonellosis and can be the presenting sign of infection, even in the absence of cat exposure or prodromal symptoms. |
| format | Article |
| id | doaj-art-fac2616fd83b43db8ca2ece60dbb8a5e |
| institution | Directory of Open Access Journals |
| issn | 1869-5760 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| spelling | doaj-art-fac2616fd83b43db8ca2ece60dbb8a5e2025-08-19T23:48:10ZengSpringerOpenJournal of Ophthalmic Inflammation and Infection1869-57602023-03-011311610.1186/s12348-023-00334-5Central retinal vein occlusion associated with Bartonella henselae infectionSunil Bellur0Amir Ali1Nam V. Nguyen2Joshua K. Fernandes3Shilpa Kodati4National Eye Institute, National Institutes of HealthNational Eye Institute, National Institutes of HealthNational Eye Institute, National Institutes of HealthDC RetinaNational Eye Institute, National Institutes of HealthAbstract Purpose To report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection. Observation A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms but reported prior exposure to fleas. Best corrected visual acuity (BCVA) was 20/400 in the left eye. Clinical examination revealed a CRVO with atypical features including significant peripapillary exudates and peripheral vascular sheathing. Laboratory testing revealed elevated B. henselae IgG titers (1:512) with no abnormalities on hypercoagulability testing. The patient was treated with doxycycline and aflibercept with an excellent clinical response and improvement in BCVA to 20/25 in the left eye two months later. Conclusion CRVO is a rare but sight-threatening complication of ocular bartonellosis and can be the presenting sign of infection, even in the absence of cat exposure or prodromal symptoms.https://doi.org/10.1186/s12348-023-00334-5Central retinal vein occlusionMacular edemaVasculitisCat scratch diseaseOcular bartonellosisBartonella henselae |
| spellingShingle | Sunil Bellur Amir Ali Nam V. Nguyen Joshua K. Fernandes Shilpa Kodati Central retinal vein occlusion associated with Bartonella henselae infection Central retinal vein occlusion Macular edema Vasculitis Cat scratch disease Ocular bartonellosis Bartonella henselae |
| title | Central retinal vein occlusion associated with Bartonella henselae infection |
| title_full | Central retinal vein occlusion associated with Bartonella henselae infection |
| title_fullStr | Central retinal vein occlusion associated with Bartonella henselae infection |
| title_full_unstemmed | Central retinal vein occlusion associated with Bartonella henselae infection |
| title_short | Central retinal vein occlusion associated with Bartonella henselae infection |
| title_sort | central retinal vein occlusion associated with bartonella henselae infection |
| topic | Central retinal vein occlusion Macular edema Vasculitis Cat scratch disease Ocular bartonellosis Bartonella henselae |
| url | https://doi.org/10.1186/s12348-023-00334-5 |
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