Skin abscess caused by Trueperella bernardiae: Case report and literature review

We investigated a skin abscess caused by Trueperella bernardiae in a patient with comorbidities. Initial empirical therapy with Clindamycin did not yield a response, and follow-up culture revealed the presence of T. bernardiae through MALDI-TOF and NGS. Since no CLSI or FDA breakpoints have been pub...

全面介紹

書目詳細資料
發表在:IDCases
Main Authors: Rasha M. Abddelgader, Sarvenaz Karamooz, Hosoon Choi, Munok Hwang, Chetan Jinadatha, Dhammika H. Navarathna
格式: Article
語言:英语
出版: Elsevier 2024-01-01
主題:
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2214250924000611
實物特徵
總結:We investigated a skin abscess caused by Trueperella bernardiae in a patient with comorbidities. Initial empirical therapy with Clindamycin did not yield a response, and follow-up culture revealed the presence of T. bernardiae through MALDI-TOF and NGS. Since no CLSI or FDA breakpoints have been published for this strain, resistant gene screening of the genetic sequence showed the presence of the erm(X) gene (with 95 % identity). This gene confers resistance to erythromycin, clindamycin, lincomycin, pristinamycin, quinupristin, and virginiamycin. Subsequent therapy with oral amoxicillin/clavulanate led to complete healing.
ISSN:2214-2509