Electrolyte Inertia In Chronic Kidney Disease

Electrolyte imbalances are a common and challengingaspect of managing chronic kidney disease (CKD). Despiteadvances in treatment, a phenomenon known as"electrolyte inertia"- the inertness to correcting abnormalelectrolyte levels- may persist in CKD patients. This inertiacan result from va...

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Bibliographic Details
Published in:Journal of the Pakistan Medical Association
Main Authors: Sourabh Sharma, Sanjay Kalra
Format: Article
Language:English
Published: Pakistan Medical Association 2025-03-01
Online Access:https://jpma.org.pk/index.php/public_html/article/view/30750
Description
Summary:Electrolyte imbalances are a common and challengingaspect of managing chronic kidney disease (CKD). Despiteadvances in treatment, a phenomenon known as"electrolyte inertia"- the inertness to correcting abnormalelectrolyte levels- may persist in CKD patients. This inertiacan result from various factors which include delayedtherapeutic intervention, the complexity of multiple coexistingcomorbidities, and the judicious balancedtherapeutic approach necessitated by the multidyselectrolytaemiain CKD management. Through theconcept of “electrolyte inertia,” we explore the underlyingcauses for this phenomenon, its clinical implications, andstrategies to overcome it, to achieve better patient care inCKD. Keywords: Chronic kidney disease, electrolytes,hyperkalaemia, hyperphosphataemia, hypocalcaemia,hyponatraemia
ISSN:0030-9982