Amyloid-like Structures in Marine Adhesive Proteins

The formation of amyloid-like structures is commonly linked to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s. However, proteins can form amyloid-like structures in non-pathological contexts, referred to as functional amyloids. We review the current knowledge on the evolutionary and...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Marine Drugs
المؤلفون الرئيسيون: Mariana Rodrigues Santos, Bárbara Joana Henriques, Romana Santos
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2025-09-01
الموضوعات:
الوصول للمادة أونلاين:https://www.mdpi.com/1660-3397/23/9/363
الوصف
الملخص:The formation of amyloid-like structures is commonly linked to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s. However, proteins can form amyloid-like structures in non-pathological contexts, referred to as functional amyloids. We review the current knowledge on the evolutionary and ecological significance of the presence of proteins presenting amyloid-like structures in adhesive secretions (both permanent and non-permanent) produced by several marine organisms; in addition, we analyze the molecular and structural properties that make them well suited for this task and their possible biomimetic and industrial applications.
تدمد:1660-3397