Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles

Abstract The tetraspanins CD9, CD81 and CD63 are major components of extracellular vesicles (EVs). Yet, their impact on EV composition remains under‐investigated. In the MCF7 breast cancer cell line CD63 was as expected predominantly intracellular. In contrast CD9 and CD81 strongly colocalized at th...

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Bibliographic Details
Published in:	Journal of Extracellular Vesicles
Main Authors:	Yé Fan, Cédric Pionneau, Federico Cocozza, Pierre‐Yves Boëlle, Solenne Chardonnet, Stéphanie Charrin, Clotilde Théry, Pascale Zimmermann, Eric Rubinstein
Format:	Article
Language:	English
Published:	Wiley 2023-08-01
Subjects:	CD63 CD81 CD9 exosomes extracellular vesicles IgSF8
Online Access:	https://doi.org/10.1002/jev2.12352

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