Evaluation of CCR5Δ32 Polymorphism in Patients with Systemic Lupus Erythematosus and Healthy Individuals

ABSTRACT Background and Objectives: C-C chemokine receptor type 5 (CCR5) is a chemokine receptor expressed at high levels on the surface of T-cells. A 32-bp deletion in the coding region of the CCR5 (CCR5Δ32) leads to production of an incomplete protein that is not expressed on the cell su...

Full description

Bibliographic Details
Published in:	Medical Laboratory Journal
Main Authors:	Zahra Heydarifard, Alijan Tabarraei, Nafiseh Abdollahi, Abdolvahab Moradi, Yosef Khanjari
Format:	Article
Language:	English
Published:	Golestan University of Medical Sciences 2018-03-01
Subjects:	ccr5 homozygote ccr5δ32 heterozygote ccr5δ32 ccr5δ32 allele sle.
Online Access:	http://mlj.goums.ac.ir/article-1-1073-en.html

Similar Items

The frequency of allele CCR5Δ32 in a Serbian population
by: Đorđević Valentina, et al.
Published: (2013-01-01)

CCR5Δ32 mutations do not determine COVID-19 disease course
by: Stefanie N. Bernas, et al.
Published: (2021-04-01)

CCR5Δ32 and HLA allele diversity in bone marrow donors from southern Brazil
by: Bruna Kulmann-Leal, et al.
Published: (2024-07-01)

The Latitude Wise Prevalence of the CCR5-Δ32-HIV Resistance Allele in India
by: Bhatnagar I, et al.
Published: (2009-01-01)

Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells
by: Laura E. P. Huyveneers, et al.
Published: (2022-09-01)

Frequency of CCR5-Δ32, CCR2-64I and SDF1-3'A alleles in HIV-infected and uninfected patients in Istanbul, Turkey
by: Muammer Osman Köksal, et al.
Published: (2021-08-01)

Pleiotropy Complicates Human Gene Editing: CCR5Δ32 and Beyond
by: Ting Li, et al.
Published: (2019-07-01)

CCR5Δ32 in Brazil: Impacts of a European Genetic Variant on a Highly Admixed Population
by: Bruna Kulmann-Leal, et al.
Published: (2021-12-01)

Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy
by: Hager Mohamed, et al.
Published: (2022-01-01)

RETRACTED: EVIDENCE OF ANCIENT HIV-1 TRANSMISSION IN THE NORTHERN EUROPE. PALAEOEPIDEMIOLOGICAL ANALYSIS
by: V. P. Sergiev
Published: (2013-12-01)

The hypothesis of non-African origin of human immunodeficiency virus type 1
by: V. P. Sergiev
Published: (2014-09-01)

Frequency of CCR5?32 Variant in North-West of Iran
by: D. Omrani
Published: (2009-06-01)

The effect of combined polymorphisms in chemokines and chemokine receptors on the clinical course of HIV-1 infection in a Brazilian population
by: Valdimara Corrêa Vieira, et al.
Published: (2011-06-01)

Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donorsResearch in context
by: Khoa Manh Dinh, et al.
Published: (2024-11-01)

The Lack of the Association of the CCR5 Genotype with the Clinical Presentation and Frequency of Tick-Borne Encephalitis in the Polish Population
by: Sambor Grygorczuk, et al.
Published: (2022-03-01)

No evidence for an association between the chemokine receptor 5 D32 polymorphism and multiple sclerosis susceptibility: A meta-analysis
by: Akbari Nazanin, et al.
Published: (2025-01-01)

High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia
by: J.A.B. Chies, et al.
Published: (2003-01-01)

Current treatment of HIV and prospects for cure
by: Werner Krause
Published: (2025-10-01)

Association of CCR2 Gene but not CCR5 Gene Polymorphisms with Alzheimer’s Disease
by: S.M. Mohaddes Ardebili
Published: (2011-06-01)

Genetic factors influencing HIV infection: a review
by: Bogusz Aksak-Wąs, et al.
Published: (2022-11-01)

The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation
by: Hütter Gero, et al.
Published: (2011-10-01)

Controversial role of smallpox on historical positive selection at the CCR5 chemokine gene (CCR5-Δ32)
by: Shailendra K. Saxena
Published: (2009-05-01)

Cenicriviroc, a dual CCR2 and CCR5 antagonist leads to a reduction in plasma fibrotic biomarkers in persons living with HIV on antiretroviral therapy
by: S. Bowler, et al.
Published: (2019-09-01)

Assembly of CCR5 with gp120 inhibits the HIV infectivity specifically in T cells
by: Joyce Appiah-Kubi, et al.
Published: (2025-07-01)

Genetic diversity and prevalence of CCR2-CCR5 gene polymorphisms in the Omani population
by: Samira H. Al-Mahruqi, et al.
Published: (2014-01-01)

Frequency of CCR5 Delta-32 Mutation in Human Immunodeficiency Virus (HIV)-seropositive and HIV-exposed Seronegative Individuals and in General Population of Medellin, Colombia
by: Francisco J Díaz, et al.
Published: (2000-04-01)

Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population
by: Munerato Patrícia, et al.
Published: (2003-01-01)

Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population
by: Patrícia Munerato, et al.

CCR5: From Natural Resistance to a New Anti-HIV Strategy
by: Lucia Lopalco
Published: (2010-02-01)

Reduced CCR5 Expression and Immune Quiescence in Black South African HIV-1 Controllers
by: Anabela C. P. Picton, et al.
Published: (2021-12-01)

ROLE OF CCR5 -2150 A>G AND Δ32 POLYMORPHISMS IN RHEUMATOID ARTHRITIS: A CASE-CONTROL STUDY IN A SICILIAN POPULATION
by: Simona Alibrandi
Published: (2017-05-01)

Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians
by: Angelica B.W. Boldt, et al.
Published: (2009-01-01)

CCL5/CCR5 axis in human diseases and related treatments
by: Zhen Zeng, et al.
Published: (2022-01-01)

Frequency of CCR5delta32 in Brazilian populations
by: A.E. Vargas, et al.
Published: (2006-03-01)

Implicación del alelo CCR5-Δ32 en la progresión clínica de pacientes VIH-1+ en Yucatán, México CCR5-Δ32 allele involvement in the clinical evolution of HIV1+ patients in Yucatán, Mexico
by: Nina Valadez-González, et al.
Published: (2011-12-01)

CCR5 Promoter Polymorphism −2459G > A: Forgotten or Ignored?
by: Rajeev K. Mehlotra
Published: (2019-06-01)

CCL5 rs2107538 Polymorphism Increased the Risk of Tuberculosis in a Sample of Iranian Population
by: Hamid Reza Kouhpayeh, et al.
Published: (2016-01-01)

Entanglement of CCR5 and Alzheimer’s Disease
by: Tianwen Li, et al.
Published: (2019-08-01)

Profil Ekspresi Koreseptor Human Immunodeficiency Virus CCR5 dan CXCR4 pada penderita Infeksi Human Immunodeficiency Virus yang menggunakan Narkoba Suntik
by: Agnes Rengga Indrati, et al.
Published: (2018-09-01)

CCR5 as a Coreceptor for Human Immunodeficiency Virus and Simian Immunodeficiency Viruses: A Prototypic Love-Hate Affair
by: Anna J. Jasinska, et al.
Published: (2022-01-01)