Pruritus as a Presenting Symptom of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia

• 發表在: Journal of Blood Medicine
• Main Authors: Abu-Tineh M, Aljaloudi E, Yassin MA
• 格式: Article
• 語言: 英语
• 出版: Dove Medical Press 2021-12-01
• 主題: chronic eosinophilic leukemia; fip1l1-pdgfra; eosinophilia; imatinib
• 在線閱讀: https://www.dovepress.com/pruritus-as-a-presenting-symptom-of-fip1l1-pdgfra-positive-chronic-eos-peer-reviewed-fulltext-article-JBM
• ISSN: 1179-2736

Mohammad Abu-Tineh,1 Esra’a Aljaloudi,2 Mohamed A Yassin1 1Department of Oncology- Hematology and BMT Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar; 2Department of Family Medicine, Hamad Medical Corporation, Doha, QatarCorrespondence: Mohammad Abu-TinehDepartment of Oncology- Hematology and BMT Section- National Center for Cancer Care and Research, Hamad Medical Corporation, Alrayan Street, Doha, QatarTel [phone]Email [e-mail]: Eosinophilia can be found in a variety of benign and malignant conditions, and a persistent eosinophilic count of more than 1500/mm3 necessitates additional investigation. Patients with FIP1L1-PDGFRA-positive chronic eosinophilic leukemia might present as asymptomatic or in a catastrophic state with multi-organ involvement. We present the case of a young male patient who was diagnosed with FIP1L1-PDGFRA chronic eosinophilic leukemia after a long history of recurrent cutaneous symptoms with no systemic signs.Keywords: chronic eosinophilic leukemia, FIP1L1-PDGFRA, eosinophilia, imatinib