Case Report: Intestinal metastasis from ALK-rearranged pulmonary pleomorphic carcinomas mimicking inflammatory myofibroblastic tumors

Lung carcinomas usually spread to the liver, lungs, pleura, pericardium, adrenal glands, brain, and bones. Anaplastic lymphoma kinase gene (ALK) fusion occurs in approximately 5% of non-small cell lung cancer (NSCLC) cases and most frequently in adenocarcinoma. Here, we report a rare case of intesti...

Full description

Bibliographic Details
Published in:	Frontiers in Oncology
Main Authors:	Changle Shi, Yan Qiu, Kang He, Yuli Li, Qingsong Wan, Jin Yao, Hongying Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	ALK inflammatory myofibroblastic tumor epithelioid inflammatory myofibroblastic sarcoma lung carcinoma intestinal metastasis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1496752/full

Similar Items

Thoracic epithelioid inflammatory myofibroblastic sarcoma: a rare and aggressive disease with case report and literature review
by: Linke Yang, et al.
Published: (2024-09-01)

Mediastinal epithelioid inflammatory myofibroblastic sarcoma with the EML4‐ALK fusion: A case report and literature review
by: Tingyu Pan, et al.
Published: (2024-01-01)

A case report: Pathological complete response to neoadjuvant lorlatinib for Epithelioid inflammatory myofibroblastic sarcoma with EML4-ALK rearrangement
by: Yang Zheng, et al.
Published: (2024-07-01)

Inflammatory myofibroblastic tumor of female genital tract with unusual features and potential diagnostic pitfalls
by: Huibin Zhang, et al.
Published: (2025-10-01)

Epithelioid inflammatory myofibroblastic sarcoma – A rare case report
by: Dona Maria George, et al.
Published: (2024-03-01)

ALK-negative inflammatory myofibroblastic tumor of the lung: A case report
by: Enze Wang, et al.
Published: (2025-04-01)

Case Report: Ensartinib for gastric epithelioid inflammatory myofibrosarcoma with STRN-ALK fusion
by: XiaoQing Li, et al.
Published: (2023-10-01)

Radiologic findings of an adolescent epithelioid inflammatory myofibroblastic sarcoma
by: David Zezoff, DO, et al.
Published: (2024-12-01)

Primary epithelioid inflammatory myofibroblastic sarcoma of the brain with fusion mimicking intra-axial glioma: a case report and brief literature review
by: Eric Eunshik Kim, et al.
Published: (2024-05-01)

Epithelioid inflammatory myofibroblastic sarcoma treated with Alectinib: a case report and literature review
by: Xinchun Wu, et al.
Published: (2024-08-01)

Inflammatory Myofibroblastic Tumor of the Upper Airways Harboring a New TRAF3-ALK Fusion Transcript
by: Valentina Di Ruscio, et al.
Published: (2021-06-01)

Placenta-associated uterine inflammatory myofibroblastic tumor with a novel FBLN1-ALK1 fusion
by: Jaclyn C. Watkins, et al.
Published: (2022-06-01)

Inflammatory myofibroblastic tumor of the submandibular gland Harboring MSN-ALK gene fusion: A case report and literature review
by: Limei Diao, et al.
Published: (2023-12-01)

New Perspectives in the Treatment of Inflammatory Myofibroblastic Tumor with ALK Translocation: Case Report
by: Johana Benedetti Pedroza, et al.
Published: (2024-07-01)

Epithelioid Fibrous Histiocytoma with <i>CARS-ALK</i> Fusion: First Case Report
by: Léo-Paul Secco, et al.
Published: (2023-01-01)

Renal Inflammatory Myofibroblastic Tumor in an Infant: Case Report with Review of Literature
by: Vinayak Dave, et al.

Uterine leiomyoma-like inflammatory myofibroblastic tumour with a rare ALK::SYN3 fusion: a clinicopathologic and molecular analysis
by: Cao Ma, et al.
Published: (2025-08-01)

Case report: Musculoskeletal metastastic inflammatory myofibroblastic tumor (IMT) treated by sequential ALK-TKI with longterm response
by: Thomas Cochin, et al.
Published: (2025-01-01)

Case Report: Clinical response to anaplastic lymphoma kinase inhibitor-based targeted therapy in uterine inflammatory myofibroblastic tumor harboring ALK-IGFBP5 fusion
by: Ting Zhao, et al.
Published: (2023-03-01)

Novel PLEC-EML4-ALK Double Fusion Underlying Crizotinib Resistance in a Metastatic Inflammatory Myofibroblastic Tumor: A Case Report
by: Alessandra Maleddu, MD, et al.
Published: (2025-05-01)

Novel ALK gene mutation in inflammatory myofibroblastic tumor of the thyroid: a case report
by: Yang Guangxu, et al.
Published: (2025-06-01)

The CT and pathological features of intestinal inflammatory myofibroblastic tumor
by: Ming Zhou, et al.
Published: (2024-09-01)

Podcast on Emerging Treatment Options for Pediatric Patients with ALK-Positive Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumors
by: Eric Lowe, et al.
Published: (2024-04-01)

Inflammatory myofibroblastic tumor of kidney with heterotopic bone formation: An unusual case mimicking a renal malignancy
by: Pooja Navale, et al.
Published: (2013-01-01)

Rare giant epithelioid inflammatory myofibroblastic sarcoma of the abdominal cavity in a child: a case report and review of the literature
by: Jinzhou Li, et al.
Published: (2024-12-01)

Spontaneous Regression of an Inflammatory Myofibroblastic Tumor: A Case Report and a Review of the Literature
by: Bianca Medici, et al.
Published: (2024-10-01)

Surgical treatment of uterine inflammatory myofibroblastic tumor with local invasion: A case report
by: Dan Mu, et al.
Published: (2025-02-01)

Inflammatory myofibroblastic tumors in children: clinical characteristics and treatment outcomes with a focus on targeted therapies
by: Ülkü Miray Yıldırım, et al.
Published: (2025-02-01)

Abdominopelvic inflammatory myofibroblastic tumor that metastasized to the vertebrae and liver: A case report and review of the literature
by: Sharon Kim, et al.
Published: (2015-04-01)

Case Report: Clinical response of ensartinib for inflammatory myofibroblastic tumor of the urinary bladder with multiple metastases and TPM4-ALK fusion
by: Hongtao Ren, et al.
Published: (2025-05-01)

Sigmoid epithelioid inflammatory myofibroblastic sarcoma with high white blood cell count: A case report
by: Dongning Liu, et al.
Published: (2020-08-01)

Inflammatory Myofibroblastic Tumor
by: R. Hodan, et al.
Published: (2006-12-01)

Inflammatory myofibroblastic tumor of the pleura with adjacent chest wall invasion and metastasis to the kidney: a case report
by: Yong-sub Na, et al.
Published: (2018-09-01)

Myofibroblastic sarcoma in breast: a case report and literature review
by: Zixi Deng, et al.
Published: (2024-05-01)

Inflammatory myofibroblastic tumour: A case report and a clinical update
by: Neelam N. Andrade, et al.
Published: (2017-09-01)

A case of inflammatory myofibroblastic tumor harboring EML4‐ALK fusion with a brain metastasis responding to alectinib
by: Soichiro Sakoda, et al.
Published: (2024-02-01)

Inflammatory myofibroblastic tumor of the lung: a comprehensive narrative review of clinical and therapeutic insights
by: Vasileios Leivaditis, et al.
Published: (2025-03-01)

Pneumothorax during Alectinib Treatment for a Uterine Inflammatory Myofibroblastic Tumor with Lung Metastasis
by: Chang-Ting Lin, et al.
Published: (2023-04-01)

Inflammatory myofibroblastic tumor of the thyroid gland
by: Yiyang Zhang, et al.
Published: (2023-05-01)

Inflammatory myofibroblastic tumors in children: a single-center retrospective study of clinical features, management, and outcomes
by: FeiYue Guo, et al.
Published: (2025-09-01)