Biophysical Control of the Glioblastoma Immunosuppressive Microenvironment: Opportunities for Immunotherapy
GBM is the most aggressive and common form of primary brain cancer with a dismal prognosis. Current GBM treatments have not improved patient survival, due to the propensity for tumor cell adaptation and immune evasion, leading to a persistent progression of the disease. In recent years, the tumor mi...
| Published in: | Bioengineering |
|---|---|
| Main Authors: | Landon Teer, Kavitha Yaddanapudi, Joseph Chen |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-5354/11/1/93 |
Similar Items
The immunosuppressive microenvironment and immunotherapy in human glioblastoma
by: Xuehua Zhang, et al.
Published: (2022-11-01)
by: Xuehua Zhang, et al.
Published: (2022-11-01)
Myeloidcells in the immunosuppressive microenvironment in glioblastoma: The characteristics and therapeutic strategies
by: Boyuan Huang, et al.
Published: (2023-02-01)
by: Boyuan Huang, et al.
Published: (2023-02-01)
Emerging insights into the immunosuppressive tumor microenvironment and its implications for glioblastoma immunotherapy
by: Niovi Nicolaou, et al.
Published: (2025-10-01)
by: Niovi Nicolaou, et al.
Published: (2025-10-01)
Unraveling the immunosuppressive microenvironment of glioblastoma and advancements in treatment
by: Dongxin Jiang, et al.
Published: (2025-05-01)
by: Dongxin Jiang, et al.
Published: (2025-05-01)
Biomimetic nanoparticles directly remodel immunosuppressive microenvironment for boosting glioblastoma immunotherapy
by: Tingting Wang, et al.
Published: (2022-10-01)
by: Tingting Wang, et al.
Published: (2022-10-01)
Editorial: Immunosuppression mechanisms and immunotherapy strategies in glioblastoma
by: Sihan Xiong, et al.
Published: (2024-04-01)
by: Sihan Xiong, et al.
Published: (2024-04-01)
Glioblastoma: Relationship between Metabolism and Immunosuppressive Microenvironment
by: Ainhoa Hernández, et al.
Published: (2021-12-01)
by: Ainhoa Hernández, et al.
Published: (2021-12-01)
Understanding the glioblastoma tumor microenvironment: leveraging the extracellular matrix to increase immunotherapy efficacy
by: Jimena Collado, et al.
Published: (2024-02-01)
by: Jimena Collado, et al.
Published: (2024-02-01)
Combining immunotherapy with radiotherapy for glioblastoma: recent advances and challenges
by: Yuanyang Sun, et al.
Published: (2025-05-01)
by: Yuanyang Sun, et al.
Published: (2025-05-01)
Erratum: Immunotherapy for Glioblastoma: Current Progress and Challenges
by: Frontiers Production Office
Published: (2021-10-01)
by: Frontiers Production Office
Published: (2021-10-01)
Hypoxia within the glioblastoma tumor microenvironment: a master saboteur of novel treatments
by: Lisa Feldman
Published: (2024-06-01)
by: Lisa Feldman
Published: (2024-06-01)
Developing and validating a prognostic disulfidptosis-related signature for glioblastoma: predicting radioresistance and synergestic effect with immunotherapy
by: Chen Chen, et al.
Published: (2025-03-01)
by: Chen Chen, et al.
Published: (2025-03-01)
Targeting tumor-associated macrophages for the immunotherapy of glioblastoma: Navigating the clinical and translational landscape
by: Zide Wang, et al.
Published: (2022-10-01)
by: Zide Wang, et al.
Published: (2022-10-01)
The hotspots and publication trends in glioblastoma and CAR-T immunotherapy: A bibliometric analysis
by: Zhaoming Song, et al.
Published: (2025-12-01)
by: Zhaoming Song, et al.
Published: (2025-12-01)
Immunotherapy in Glioblastoma: An Overview of Current Status
by: Sarfraz Z, et al.
Published: (2025-07-01)
by: Sarfraz Z, et al.
Published: (2025-07-01)
Insights into the glioblastoma tumor microenvironment: current and emerging therapeutic approaches
by: Dev Kumar Tripathy, et al.
Published: (2024-03-01)
by: Dev Kumar Tripathy, et al.
Published: (2024-03-01)
Epigenetics and Metabolism Reprogramming Interplay into Glioblastoma: Novel Insights on Immunosuppressive Mechanisms
by: Filippo Torrisi, et al.
Published: (2023-01-01)
by: Filippo Torrisi, et al.
Published: (2023-01-01)
Glioblastoma vaccine tumor therapy research progress
by: Tong Zhao, et al.
Published: (2022-01-01)
by: Tong Zhao, et al.
Published: (2022-01-01)
Overcoming T-cell exhaustion in glioblastoma: A narrative review
by: Xuya Wang, et al.
Published: (2022-01-01)
by: Xuya Wang, et al.
Published: (2022-01-01)
Clofazimine enhances anti-PD-1 immunotherapy in glioblastoma by inhibiting Wnt6 signaling and modulating the tumor immune microenvironment
by: Yuze Zhao, et al.
Published: (2025-03-01)
by: Yuze Zhao, et al.
Published: (2025-03-01)
The Biophysics of Flash Radiotherapy: Tools for Measuring Tumor and Normal Tissues Microenvironment
by: Islam G. Ali, et al.
Published: (2025-07-01)
by: Islam G. Ali, et al.
Published: (2025-07-01)
γδ T cells as a potential therapeutic agent for glioblastoma
by: In Kang, et al.
Published: (2023-10-01)
by: In Kang, et al.
Published: (2023-10-01)
Extracellular Vesicles in Glioblastoma Tumor Microenvironment
by: Anuroop Yekula, et al.
Published: (2020-01-01)
by: Anuroop Yekula, et al.
Published: (2020-01-01)
Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures
by: Francesca Lombardi, et al.
Published: (2024-01-01)
by: Francesca Lombardi, et al.
Published: (2024-01-01)
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy
by: Ju Huang, et al.
Published: (2023-04-01)
by: Ju Huang, et al.
Published: (2023-04-01)
Tumor antigens and immune subtypes of glioblastoma: the fundamentals of mRNA vaccine and individualized immunotherapy development
by: Changwu Wu, et al.
Published: (2022-07-01)
by: Changwu Wu, et al.
Published: (2022-07-01)
Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy
by: Areez Shafqat, et al.
Published: (2023-07-01)
by: Areez Shafqat, et al.
Published: (2023-07-01)
Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment
by: Andrea Franson, et al.
Published: (2022-09-01)
by: Andrea Franson, et al.
Published: (2022-09-01)
Immune microenvironments differ in immune characteristics and outcome of glioblastoma multiforme
by: Botao Zhang, et al.
Published: (2019-06-01)
by: Botao Zhang, et al.
Published: (2019-06-01)
Research progress on the role of PTEN deletion or mutation in the immune microenvironment of glioblastoma
by: Leiya Du, et al.
Published: (2024-08-01)
by: Leiya Du, et al.
Published: (2024-08-01)
Engineered brain‐targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma
by: Jun Yang, et al.
Published: (2025-04-01)
by: Jun Yang, et al.
Published: (2025-04-01)
Corrigendum: Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy
by: Areez Shafqat, et al.
Published: (2023-07-01)
by: Areez Shafqat, et al.
Published: (2023-07-01)
Navigating the immunosuppressive brain tumor microenvironment using spatial biology
by: Samuel S. Widodo, et al.
Published: (2024-09-01)
by: Samuel S. Widodo, et al.
Published: (2024-09-01)
Extracellular vesicles as modulators of glioblastoma progression and tumor microenvironment
by: Jie Dai, et al.
Published: (2024-02-01)
by: Jie Dai, et al.
Published: (2024-02-01)
Prospects of immune checkpoint blockade and vaccine-based immunotherapy for glioblastoma
by: Tietze Stefanie, et al.
Published: (2021-04-01)
by: Tietze Stefanie, et al.
Published: (2021-04-01)
The Role of Cytokines and Chemokines in Shaping the Immune Microenvironment of Glioblastoma: Implications for Immunotherapy
by: Erica C. F. Yeo, et al.
Published: (2021-03-01)
by: Erica C. F. Yeo, et al.
Published: (2021-03-01)
Inhibiting interferon-γ induced cancer intrinsic TNFRSF14 elevation restrains the malignant progression of glioblastoma
by: Yunhe Han, et al.
Published: (2024-07-01)
by: Yunhe Han, et al.
Published: (2024-07-01)
Immunosuppressive tumor microenvironment and advance in immunotherapy in melanoma bone metastasis
by: Yiqun Ma, et al.
Published: (2025-08-01)
by: Yiqun Ma, et al.
Published: (2025-08-01)
Immune checkpoint pathways in glioblastoma: a diverse and evolving landscape
by: Julio F. Inocencio, et al.
Published: (2024-09-01)
by: Julio F. Inocencio, et al.
Published: (2024-09-01)
The Vascular Microenvironment in Glioblastoma: A Comprehensive Review
by: Alejandra Mosteiro, et al.
Published: (2022-05-01)
by: Alejandra Mosteiro, et al.
Published: (2022-05-01)
Similar Items
-
The immunosuppressive microenvironment and immunotherapy in human glioblastoma
by: Xuehua Zhang, et al.
Published: (2022-11-01) -
Myeloidcells in the immunosuppressive microenvironment in glioblastoma: The characteristics and therapeutic strategies
by: Boyuan Huang, et al.
Published: (2023-02-01) -
Emerging insights into the immunosuppressive tumor microenvironment and its implications for glioblastoma immunotherapy
by: Niovi Nicolaou, et al.
Published: (2025-10-01) -
Unraveling the immunosuppressive microenvironment of glioblastoma and advancements in treatment
by: Dongxin Jiang, et al.
Published: (2025-05-01) -
Biomimetic nanoparticles directly remodel immunosuppressive microenvironment for boosting glioblastoma immunotherapy
by: Tingting Wang, et al.
Published: (2022-10-01)
