Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome
Abstract Extracellular vesicles (EVs) in plasma are composed of exosomes, microvesicles, and apoptotic bodies. We report a plasma EV enrichment strategy using magnetic beads called Mag-Net. Proteomic interrogation of this plasma EV fraction enables the detection of proteins that are beyond the dynam...
| 發表在: | Nature Communications |
|---|---|
| Main Authors: | Christine C. Wu, Kristine A. Tsantilas, Jea Park, Deanna Plubell, Justin A. Sanders, Previn Naicker, Ireshyn Govender, Sindisiwe Buthelezi, Stoyan Stoychev, Justin Jordaan, Gennifer Merrihew, Eric Huang, Edward D. Parker, Michael Riffle, Andrew N. Hoofnagle, William S. Noble, Kathleen L. Poston, Thomas J. Montine, Michael J. MacCoss |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Nature Portfolio
2025-07-01
|
| 在線閱讀: | https://doi.org/10.1038/s41467-025-60595-7 |
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