Indoleamine 2,3-dioxygenase (IDO): Only an enzyme or a checkpoint controller?
Tryptophan (Trp) is one of the important essential amino acids and Kynurenine pathway (KP) is the first and rate limiting step of degrading Trp to active metabolites. Recent studies showed that KP metabolites have antimicrobial and immunosuppressive roles. The main controller enzyme of this pathway...
| 發表在: | Journal of Oncological Sciences |
|---|---|
| Main Authors: | Cemil Bilir, M.D., Can Sarisozen, PhD |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Turkish Society of Oncology
2017-07-01
|
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2452336417300201 |
相似書籍
TRYPTOPHAN AND INDOLEAMINE-2,3-DIOXYGENASE (IDO) IN PATHOGENESIS OF IMMUNOSUPPRESSIVE CLINICAL CONDITIONS
由: V. A. Kozlov, et al.
出版: (2017-07-01)
由: V. A. Kozlov, et al.
出版: (2017-07-01)
Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice
由: Nao Hirata, et al.
出版: (2018-09-01)
由: Nao Hirata, et al.
出版: (2018-09-01)
Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy
由: Pengbo Yang, et al.
出版: (2023-07-01)
由: Pengbo Yang, et al.
出版: (2023-07-01)
The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance
由: Knut A. Hestad, et al.
出版: (2017-10-01)
由: Knut A. Hestad, et al.
出版: (2017-10-01)
The Two Sides of Indoleamine 2,3-Dioxygenase 2 (IDO2)
由: Chiara Suvieri, et al.
出版: (2024-11-01)
由: Chiara Suvieri, et al.
出版: (2024-11-01)
Significance of Indoleamine 2,3-Dioxygenase Expression in the Immunological Response of Kidney Graft Recipients
由: Krzysztof Wiśnicki, et al.
出版: (2022-09-01)
由: Krzysztof Wiśnicki, et al.
出版: (2022-09-01)
Increased Indoleamine 2,3-Dioxygenase 1 (IDO-1) Activity and Inflammatory Responses during Chikungunya Virus Infection
由: Thiara Manuele Alves de Souza, et al.
出版: (2022-04-01)
由: Thiara Manuele Alves de Souza, et al.
出版: (2022-04-01)
Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0
由: Yvonne Grobben, et al.
出版: (2021-01-01)
由: Yvonne Grobben, et al.
出版: (2021-01-01)
Indoleamine 2,3 dioxygenase (IDO) level as a marker for significant coronary artery disease
由: Nattawut Wongpraparut, et al.
出版: (2021-07-01)
由: Nattawut Wongpraparut, et al.
出版: (2021-07-01)
Regulation of the Immune Checkpoint Indoleamine 2,3-Dioxygenase Expression by Epstein–Barr Virus
由: Leila Sawada, et al.
出版: (2021-11-01)
由: Leila Sawada, et al.
出版: (2021-11-01)
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients
由: Andrea Stieger, et al.
出版: (2024-06-01)
由: Andrea Stieger, et al.
出版: (2024-06-01)
Indoleamine 2,3- Dioxygenase: A Novel Immunotherapeutic Target for Osteosarcoma
由: Asim Farooq, et al.
出版: (2022-09-01)
由: Asim Farooq, et al.
出版: (2022-09-01)
Progesterone decreased indoleamine 2,3-dioxygenase 1(IDO1) expression in early pregnancy chorionic villi and decidua
由: Minyan Yang, et al.
出版: (2021-04-01)
由: Minyan Yang, et al.
出版: (2021-04-01)
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells
由: Hannah Jonescheit, et al.
出版: (2020-05-01)
由: Hannah Jonescheit, et al.
出版: (2020-05-01)
Indoleamine 2,3-dioxygenase expression in patients with allergic rhinitis: a case-control study
由: Luukkainen Annika, et al.
出版: (2011-12-01)
由: Luukkainen Annika, et al.
出版: (2011-12-01)
An Expanded Neuroimmunomodulation Axis: sCD83-Indoleamine 2,3-Dioxygenase—Kynurenine Pathway and Updates of Kynurenine Pathway in Neurologic Diseases
由: Li Bo, et al.
出版: (2018-06-01)
由: Li Bo, et al.
出版: (2018-06-01)
Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product
由: Hongchuan Zhao, et al.
出版: (2019-03-01)
由: Hongchuan Zhao, et al.
出版: (2019-03-01)
Kynurenines as a Novel Target for the Treatment of Inflammatory Disorders
由: Adrian Mor, et al.
出版: (2024-07-01)
由: Adrian Mor, et al.
出版: (2024-07-01)
Indoleamine 2,3-Dioxygenase Is Involved in Interferon Gamma’s Anti-BKPyV Activity in Renal Cells
由: Tony Fiore, et al.
出版: (2020-08-01)
由: Tony Fiore, et al.
出版: (2020-08-01)
Research progress of indoleamine 2,3-dioxygenase 1 in gastric cancer
由: Pei Xiaxia, et al.
出版: (2023-03-01)
由: Pei Xiaxia, et al.
出版: (2023-03-01)
IDO Expression in Cancer: Different Compartment, Different Functionality?
由: Annabel Meireson, et al.
出版: (2020-09-01)
由: Annabel Meireson, et al.
出版: (2020-09-01)
Indoleamine 2,3-Dioxygenase as a Therapeutic Target for Alzheimer’s Disease and Geriatric Depression
由: Karl Savonije, et al.
出版: (2023-05-01)
由: Karl Savonije, et al.
出版: (2023-05-01)
Discovery of cyanopyridine scaffold as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors through virtual screening and preliminary hit optimisation
由: Xi Xu, et al.
出版: (2019-01-01)
由: Xi Xu, et al.
出版: (2019-01-01)
What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?
由: Theodoros Eleftheriadis
出版: (2018-08-01)
由: Theodoros Eleftheriadis
出版: (2018-08-01)
The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy
由: Lilla Hornyák, et al.
出版: (2018-01-01)
由: Lilla Hornyák, et al.
出版: (2018-01-01)
Kynurenines as a Novel Target for the Treatment of Malignancies
由: Adrian Mor, et al.
出版: (2021-06-01)
由: Adrian Mor, et al.
出版: (2021-06-01)
IDO-Mediated Immune and Metabolic Dysregulation in Schwann Cells Exposed to <i>Mycobacterium leprae</i>
由: Atta Ur Rahman, et al.
出版: (2025-10-01)
由: Atta Ur Rahman, et al.
出版: (2025-10-01)
Inhibitory effect of human indoleamine 2,3-dioxygenase 1 (hIDO1) by kazinols of 1,3-diphenylpropane derivatives
由: Taehoon Oh, et al.
出版: (2024-09-01)
由: Taehoon Oh, et al.
出版: (2024-09-01)
First-in-Class, Thiosemicarbazide-Based, Dual Inhibitors of Human DNA Topoisomerase IIα and Indoleamine-2,3-Dioxygenase 1 (IDO-1) with Strong Anticancer Properties
由: Barbara Kaproń, et al.
出版: (2022-11-01)
由: Barbara Kaproń, et al.
出版: (2022-11-01)
Indoleamine 2,3‐dioxygenase gene expression and kynurenine to tryptophan ratio correlation with nasopharyngeal carcinoma progression and survival
由: Sameh Souissi, et al.
出版: (2022-09-01)
由: Sameh Souissi, et al.
出版: (2022-09-01)
Contribution of indoleamine 2,3-dioxygenase in preeclampsia
由: Mona F.M El-Karn, et al.
出版: (2016-01-01)
由: Mona F.M El-Karn, et al.
出版: (2016-01-01)
Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease
由: Nóra Török, et al.
出版: (2022-09-01)
由: Nóra Török, et al.
出版: (2022-09-01)
Immunomodulatory Factors in Primary Endometrial Cell Cultures Isolated from Cancer and Noncancerous Human Tissue–Focus on RAGE and IDO1
由: Joanna Tkaczuk-Włach, et al.
出版: (2021-04-01)
由: Joanna Tkaczuk-Włach, et al.
出版: (2021-04-01)
Expression of Indoleamine 2,3-Dioxygenase Induced by IFN-γ and TNF-α as Potential Biomarker of Prostate Cancer Progression
由: Irina Banzola, et al.
出版: (2018-05-01)
由: Irina Banzola, et al.
出版: (2018-05-01)
Involvement of the tryptophan-kynurenine pathway in the pathogenesis of autoimmune diseases
由: A-Yuan Chen, et al.
出版: (2025-10-01)
由: A-Yuan Chen, et al.
出版: (2025-10-01)
Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis
由: Camilla Grønkjær Jensen, et al.
出版: (2021-07-01)
由: Camilla Grønkjær Jensen, et al.
出版: (2021-07-01)
IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection
由: Rafaella Oliveira dos Santos, et al.
出版: (2025-07-01)
由: Rafaella Oliveira dos Santos, et al.
出版: (2025-07-01)
Serum indoleamine 2,3-dioxygenase level and diagnostic value in patients with rosacea
由: Merve Sena Odabasi, et al.
出版: (2023-01-01)
由: Merve Sena Odabasi, et al.
出版: (2023-01-01)
Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity
由: Mincheol Kwon, et al.
出版: (2019-01-01)
由: Mincheol Kwon, et al.
出版: (2019-01-01)
DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota
由: Li-Ping Zhao, et al.
出版: (2023-01-01)
由: Li-Ping Zhao, et al.
出版: (2023-01-01)
相似書籍
-
TRYPTOPHAN AND INDOLEAMINE-2,3-DIOXYGENASE (IDO) IN PATHOGENESIS OF IMMUNOSUPPRESSIVE CLINICAL CONDITIONS
由: V. A. Kozlov, et al.
出版: (2017-07-01) -
Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice
由: Nao Hirata, et al.
出版: (2018-09-01) -
Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy
由: Pengbo Yang, et al.
出版: (2023-07-01) -
The Relationships among Tryptophan, Kynurenine, Indoleamine 2,3-Dioxygenase, Depression, and Neuropsychological Performance
由: Knut A. Hestad, et al.
出版: (2017-10-01) -
The Two Sides of Indoleamine 2,3-Dioxygenase 2 (IDO2)
由: Chiara Suvieri, et al.
出版: (2024-11-01)
