Indoleamine 2,3-dioxygenase (IDO): Only an enzyme or a checkpoint controller?

Tryptophan (Trp) is one of the important essential amino acids and Kynurenine pathway (KP) is the first and rate limiting step of degrading Trp to active metabolites. Recent studies showed that KP metabolites have antimicrobial and immunosuppressive roles. The main controller enzyme of this pathway...

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Bibliographic Details
Published in:	Journal of Oncological Sciences
Main Authors:	Cemil Bilir, M.D., Can Sarisozen, PhD
Format:	Article
Language:	English
Published:	Turkish Society of Oncology 2017-07-01
Subjects:	Indoleamine 2,3-dioxygenase Kynurenine pathway Cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452336417300201

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