A study of somatic BRCA variants and their putative effect on protein properties in malignant mesothelioma

The aim of this study is to analyze the prevalence of somatic mutations in BRCA1 and BRCA2 in malignant mesothelioma and their putative impact on protein properties.

Bibliographic Details
Published in:	Pleura and Peritoneum
Main Authors:	Krishnamurthy Kritika, Oh Kei Shing, Alghamdi Sarah, Sriganeshan Vathany, Poppiti Robert
Format:	Article
Language:	English
Published:	De Gruyter 2023-03-01
Subjects:	brca brca1 brca2 disorder of proteins malignant mesothelioma somatic variants
Online Access:	https://doi.org/10.1515/pp-2023-0003

Similar Items

Prevalence of BRCA1 and BRCA2 germline variants in an unselected pancreatic cancer patient cohort in Pakistan
by: Noor Muhammad, et al.
Published: (2023-11-01)

Oncotype DX Recurrence Score and Germline BRCA Variants in Patients with HR-Positive/HER2-Negative Early Breast Cancer: A Retrospective Observational Study
by: Stefania Morganti, et al.
Published: (2025-04-01)

BRCA1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancer
by: Caroline Stahnke Richau, et al.
Published: (2024-02-01)

Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations
by: Avantika Lal, et al.
Published: (2019-06-01)

Prostate screening uptake in Australian <it>BRCA1 </it>and <it>BRCA2 </it>carriers
by: McKinley Joanne M, et al.
Published: (2007-09-01)

Prostate Cancer: Germline Mutations in BRCA1 and BRCA2
by: Pankaja Umarane, et al.
Published: (2023-03-01)

Turkish population-based screening for first identified changes of BRCA1 and BRCA2 genes in breast and/or ovarian cancer patients
by: Tuğba Semerci Sevimli, et al.
Published: (2024-04-01)

Serum testosterone and prostate cancer in men with germline BRCA1/2 pathogenic variants
by: Alexander Dias, et al.
Published: (2023-05-01)

A study of The Frequency and Type of Mutation in Exon 11 in BRCA1 and BRCA2 Genes In Breast Cancer Women With Positive Family History
by: Noor Jassim M, et al.
Published: (2018-06-01)

A study of The Frequency and Type of Mutation in Exon 11 in BRCA1 and BRCA2 Genes In Breast Cancer Women With Positive Family History
by: Noor Jassim M, et al.
Published: (2018-06-01)

Germline and somatic mutational variants of Tunisian high grade serous ovarian cancer identified by next-generation sequencing
by: Nihel Ammous-Boukhris, et al.
Published: (2025-10-01)

Prevalence of Somatic BRCA1 and BRCA2 Mutations in Ovarian Cancer among Filipinos using Next Generation Sequencing
by: Charles Joseph Bernardo, et al.
Published: (2023-05-01)

Somatic BRCA Mutation in High Grade Epithelial Ovarian Cancer Patients
by: Tarinee Manchana, et al.
Published: (2019-01-01)

Sequence Variants of BRCA1 and BRCA2 Genes in Four Iranian Families with Breast and Ovarian Cancer
by: F Keshavarzi, et al.
Published: (2011-06-01)

BRCA genes as candidates for colorectal cancer genetic testing panel: systematic review and meta-analysis
by: Zhewen Feng, et al.
Published: (2023-08-01)

Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health
by: Stephanie Andaluz, et al.
Published: (2024-04-01)

Risk of metastasis in BRCA2 carriers diagnosed with triple‐negative breast cancer
by: Marcelo Moreno, et al.
Published: (2023-08-01)

Prophylactic adnexectomy in BRCA1 and BRCA2 gene mutation carriers (а review of literature)
by: T. A. Shendrikova, et al.
Published: (2014-07-01)

BRCA-associated hereditary male cancers: can gender affect the prevalence and spectrum of germline pathogenic variants?
by: Daniele Fanale, et al.
Published: (2024-06-01)

The known genetic variants of BRCA1, BRCA2 and NOD2 in pancreatitis and pancreatic cancer risk assessment
by: Jarosław Matykiewicz, et al.
Published: (2025-01-01)

Tumour Versus Germline <i>BRCA</i> Testing in Ovarian Cancer: A Single-Site Institution Experience in the United Kingdom
by: Iolia Akaev, et al.
Published: (2021-03-01)

Molecular analysis of BRCA1 and BRCA2 genes in La Rioja (Spain): five new variants
by: Raquel Salazar Saez, et al.
Published: (2024-10-01)

Limited Independent Follow-Up with Germline Testing of Variants Detected in BRCA1 and BRCA2 by Tumor-Only Sequencing
by: Carol J. Nowlen, et al.
Published: (2024-02-01)

Study of the Carrier State for Five BRCA1/BRCA2 Deleterious Mutations in Bulgarian Women with Breast Cancer
by: Katia Kovacheva, et al.
Published: (2013-12-01)

Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
by: Yomali Ferreyra, et al.
Published: (2023-08-01)

Association Between Germline BRCA1/2 Gene Variants and Clinicopathological Features of Ovarian Cancer
by: Luo Y, et al.
Published: (2024-01-01)

Dermatological and Dermoscopic Baselines in BRCA Mutation Carriers
by: Giovanni Paolino, et al.
Published: (2022-04-01)

MANAGEMENT OF BREAST CANCER WITH BRCA GENE MUTATION
by: I Wayan Ari Sumardika, et al.
Published: (2013-09-01)

Comparison of suspected Lynch syndrome patients carrying BRCA and BRCA‐like variants with Lynch syndrome probands: Phenotypic characteristics and pedigree analyses
by: Yun Xu, et al.
Published: (2020-08-01)

Histopathological characterization of carcinoma breast with BRCA1/2 sequence variation in a Tertiary Care Center in Kerala, South India
by: Reeba Mary Issac, et al.
Published: (2022-01-01)

Regional Differences in the Frequency of BRCA1 and BRCA2 Variants in Northeastern Japan: A Cohort Study
by: Hidekazu Shirota, et al.
Published: (2025-04-01)

Different Mechanisms in Doxorubicin-Induced Cardiomyopathy: Impact of BRCA1 and BRCA2 Mutations
by: Hien C. Nguyen, et al.
Published: (2024-01-01)

Risk-Reducing Options for High-Grade Serous Gynecologic Malignancy in BRCA1/2
by: Lauren Clarfield, et al.
Published: (2022-03-01)

Role of BRCA 1 и BRCA 2 gene mutations in the occurrence of male breast cancer
by: A. V. Bykova, et al.
Published: (2014-07-01)

Druggable Molecular Networks in <i>BRCA1/BRCA2</i>-Mutated Breast Cancer
by: Francesca Pia Carbone, et al.
Published: (2025-03-01)

The Landscape of BRCA Mutations among Egyptian Women with Breast Cancer
by: Hamdy A. Azim, et al.
Published: (2023-09-01)

Reclassification of VUS in BRCA1 and BRCA2 using the new BRCA1/BRCA2 ENIGMA track set demonstrates the superiority of ClinGen ENIGMA Expert Panel specifications over the standard ACMG/AMP classification system
by: Anna Benet-Pagès, et al.
Published: (2025-01-01)

Germline mutations in BRCA1 and BRCA2 among Brazilian women with ovarian cancer treated in the Public Health System
by: Caroline de Oliveira Ferreira, et al.
Published: (2024-04-01)

Genetic Variation of The BRCA1 and BRCA2 Genes in Macedonian Patients
by: Plaseska-Karanfilska Dijana, et al.
Published: (2012-12-01)

Effectiveness of decision aids for female BRCA1 and BRCA2 mutation carriers: a systematic review
by: Lisa Krassuski, et al.
Published: (2019-08-01)