Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives
In the present study, a series of 3-(5-cyclohexyl-1,3,4-oxadiazol-2-yl)-N-substituted aniline have been synthesized by multistep reaction scheme. Benzohydrazide was used as the starting material. The structures of all synthesized compounds are characterized and confirmed by FT-IR, 1H and C13 NMR and...
| 發表在: | Saudi Pharmaceutical Journal |
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| Main Authors: | , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Springer
2017-03-01
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| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S131901641630072X |
| 總結: | In the present study, a series of 3-(5-cyclohexyl-1,3,4-oxadiazol-2-yl)-N-substituted aniline have been synthesized by multistep reaction scheme. Benzohydrazide was used as the starting material. The structures of all synthesized compounds are characterized and confirmed by FT-IR, 1H and C13 NMR and mass spectral studies with the intention of developing the novel biologically active compounds. All title synthetic compounds were screened for their antidiabetic, anti-inflammatory and anticancer activities. |
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| ISSN: | 1319-0164 |