Status Epilepticus: A Practical Guide for Intensivists

This review explores the pathophysiology of status epilepticus in adults, along with its incidence and key clinical considerations. We present a comprehensive treatment approach, emphasizing both emergent and urgent therapies. Additionally, we examine the role of newer agents such as clobazam and br...

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Bibliographic Details
Published in:Türk Yoğun Bakim Derneği Dergisi
Main Authors: Salia Farrokh, Ivanna Joseph
Format: Article
Language:English
Published: Turkish Society of Intensive Care 2025-03-01
Subjects:
Online Access:https://www.turkishjic.org/articles/status-epilepticus-a-practical-guide-for-intensivists/doi/tybd.galenos.2025.55823
Description
Summary:This review explores the pathophysiology of status epilepticus in adults, along with its incidence and key clinical considerations. We present a comprehensive treatment approach, emphasizing both emergent and urgent therapies. Additionally, we examine the role of newer agents such as clobazam and brivaracetam. This review also includes dosing strategies and potential drug-drug interactions of commonly used antiseizure medications in critically ill patients. Treatment strategies for refractory and super-refractory status epilepticus are also discussed. Finally, we provide a practical algorithm for a structured management approach, along with dosing and titration guidelines for sedatives following seizure cessation.
ISSN:2146-6416
2147-267X