Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura
ABSTRACT This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non‐traditional triggers, particularly in patients with underlying cardiovascular...
| Published in: | Clinical Case Reports |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-10-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.71047 |
| _version_ | 1848649955899604992 |
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| author | Qutaiba Qafisheh Roaa Aljunaidi Abdalhakim Shubietah Mohammed AbuBaha Hossam Salameh Muath Baniowda Mohanad Qwaider Mohammad Alqadi Imad Hariri |
| author_facet | Qutaiba Qafisheh Roaa Aljunaidi Abdalhakim Shubietah Mohammed AbuBaha Hossam Salameh Muath Baniowda Mohanad Qwaider Mohammad Alqadi Imad Hariri |
| author_sort | Qutaiba Qafisheh |
| collection | DOAJ |
| container_title | Clinical Case Reports |
| description | ABSTRACT This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non‐traditional triggers, particularly in patients with underlying cardiovascular disease and no identifiable emotional or physical stressors. Diagnosis favored a dexamethasone‐triggered Takotsubo phenotype based on non‐obstructive coronaries, regional wall‐motion abnormalities extending beyond a single arterial territory, absence of alternate stressors, and biologic plausibility of steroid‐mediated catecholaminergic upregulation. |
| format | Article |
| id | doaj-e22708b28fed4e238c5891564eef0c83 |
| institution | Directory of Open Access Journals |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Wiley |
| record_format | Article |
| spelling | doaj-e22708b28fed4e238c5891564eef0c832025-11-03T04:12:49ZengWileyClinical Case Reports2050-09042025-10-011310n/an/a10.1002/ccr3.71047Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic PurpuraQutaiba Qafisheh0Roaa Aljunaidi1Abdalhakim Shubietah2Mohammed AbuBaha3Hossam Salameh4Muath Baniowda5Mohanad Qwaider6Mohammad Alqadi7Imad Hariri8Department of Medicine University of Toledo Toledo Ohio USAFaculty of Medicine and Health Sciences Palestine Polytechnic University Hebron PalestineDepartment of Medicine Advocate Illinois Masonic Medical Center Chicago Illinois USADepartment of Medicine An‐Najah National University Nablus PalestineDepartment of Medicine An‐Najah National University Nablus PalestineDepartment of Medicine University of Missouri–Kansas City Kansas City Missouri USADepartment of Medicine University of Toledo Toledo Ohio USADepartment of Medicine University of Toledo Toledo Ohio USAProMedica Physician Group – Cardiology Toledo Ohio USAABSTRACT This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non‐traditional triggers, particularly in patients with underlying cardiovascular disease and no identifiable emotional or physical stressors. Diagnosis favored a dexamethasone‐triggered Takotsubo phenotype based on non‐obstructive coronaries, regional wall‐motion abnormalities extending beyond a single arterial territory, absence of alternate stressors, and biologic plausibility of steroid‐mediated catecholaminergic upregulation.https://doi.org/10.1002/ccr3.71047immune thrombocytopenic purpura (ITP)steroid cardiomyopathysteroid induced TakotsuboTakotsubo cardiomyopathy |
| spellingShingle | Qutaiba Qafisheh Roaa Aljunaidi Abdalhakim Shubietah Mohammed AbuBaha Hossam Salameh Muath Baniowda Mohanad Qwaider Mohammad Alqadi Imad Hariri Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura immune thrombocytopenic purpura (ITP) steroid cardiomyopathy steroid induced Takotsubo Takotsubo cardiomyopathy |
| title | Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura |
| title_full | Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura |
| title_fullStr | Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura |
| title_full_unstemmed | Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura |
| title_short | Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura |
| title_sort | steroid induced takotsubo cardiomyopathy in a patient with immune thrombocytopenic purpura |
| topic | immune thrombocytopenic purpura (ITP) steroid cardiomyopathy steroid induced Takotsubo Takotsubo cardiomyopathy |
| url | https://doi.org/10.1002/ccr3.71047 |
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