HAZ, a novel peptide with broad-spectrum antibacterial activity
Objective: The growing microbial resistance to antibiotics is a global public concern, which creates serious needs for newer antimicrobial agents. Antimicrobial peptides (AMPs) are increasingly exploited in drug development as therapeutic candidates. Here, we aimed to design and characterize a novel...
| Published in: | Saudi Pharmaceutical Journal |
|---|---|
| Main Authors: | Mohammad Alsaggar, Mohammad Al-Hazabreh, Yara Al Tall, Alaa Al-Tarawneh, Ruba S. Darweesh, Majed Masadeh |
| Format: | Article |
| Language: | English |
| Published: |
Springer
2022-11-01
|
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016422002316 |
Similar Items
Design and characterization of a new hybrid peptide from LL-37 and BMAP-27
by: Al Tall Y, et al.
Published: (2019-04-01)
by: Al Tall Y, et al.
Published: (2019-04-01)
Synergistic Antibacterial Efficacy of Melittin in Combination with Oxacillin against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)
by: Ana Flávia Marques Pereira, et al.
Published: (2023-11-01)
by: Ana Flávia Marques Pereira, et al.
Published: (2023-11-01)
Synthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
by: Arif Iftikhar Khan, et al.
Published: (2024-08-01)
by: Arif Iftikhar Khan, et al.
Published: (2024-08-01)
CancerGram: An Effective Classifier for Differentiating Anticancer from Antimicrobial Peptides
by: Michał Burdukiewicz, et al.
Published: (2020-10-01)
by: Michał Burdukiewicz, et al.
Published: (2020-10-01)
Complementary Activities of Host Defence Peptides and Antibiotics in Combating Antimicrobial Resistant Bacteria
by: Patrick R. Lennard, et al.
Published: (2023-10-01)
by: Patrick R. Lennard, et al.
Published: (2023-10-01)
Developing antibacterial peptides as a promising therapy for combating antibiotic-resistant Pseudomonas aeruginosa infections
by: Rula M. Darwish, et al.
Published: (2024-06-01)
by: Rula M. Darwish, et al.
Published: (2024-06-01)
A3, a Scorpion Venom Derived Peptide Analogue with Potent Antimicrobial and Potential Antibiofilm Activity against Clinical Isolates of Multi-Drug Resistant Gram Positive Bacteria
by: Ammar Almaaytah, et al.
Published: (2018-07-01)
by: Ammar Almaaytah, et al.
Published: (2018-07-01)
An Overview of Antimicrobial Peptides as Anticancer Agents
by: Ali Ganji, et al.
Published: (2019-09-01)
by: Ali Ganji, et al.
Published: (2019-09-01)
Protease-Resistant, Broad-Spectrum Antimicrobial Peptides with High Antibacterial and Antifungal Activity
by: Tanil Kocagoz, et al.
Published: (2025-02-01)
by: Tanil Kocagoz, et al.
Published: (2025-02-01)
Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities
by: Anna Lucia Tornesello, et al.
Published: (2020-06-01)
by: Anna Lucia Tornesello, et al.
Published: (2020-06-01)
Discovery of a Potent Antimicrobial Peptide Through Rational Design: A New Frontier in Pathogen Control
by: Bruna Agrillo, et al.
Published: (2025-07-01)
by: Bruna Agrillo, et al.
Published: (2025-07-01)
Multifaceted Marine Peptides and Their Therapeutic Potential
by: Svetlana V. Guryanova, et al.
Published: (2025-07-01)
by: Svetlana V. Guryanova, et al.
Published: (2025-07-01)
Recent Advances in Multifunctional Antimicrobial Peptides as Immunomodulatory and Anticancer Therapy: Chromogranin A-Derived Peptides and Dermaseptins as Endogenous versus Exogenous Actors
by: Francesco Scavello, et al.
Published: (2022-09-01)
by: Francesco Scavello, et al.
Published: (2022-09-01)
Investigation of cytotoxic effect and action mechanism of a synthetic peptide derivative of rabbit cathelicidin against MDA-MB-231 breast cancer cell line
by: Marzieh Bashi, et al.
Published: (2024-06-01)
by: Marzieh Bashi, et al.
Published: (2024-06-01)
Anticancer activities of natural antimicrobial peptides from animals
by: Baozhen Qu, et al.
Published: (2024-01-01)
by: Baozhen Qu, et al.
Published: (2024-01-01)
Topoisomeric Membrane-Active Peptides: A Review of the Last Two Decades
by: Adam Carrera-Aubesart, et al.
Published: (2023-10-01)
by: Adam Carrera-Aubesart, et al.
Published: (2023-10-01)
Antibacterial and antibiofilm features of mutSMAP-18 against Vibrio cholerae
by: Ishrat Jahan, et al.
Published: (2024-11-01)
by: Ishrat Jahan, et al.
Published: (2024-11-01)
Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue
by: Haixin Qin, et al.
Published: (2023-01-01)
by: Haixin Qin, et al.
Published: (2023-01-01)
OmpH is Involved in the Decrease of Acinetobacter baumannii Biofilm by the Antimicrobial Peptide Cec4
by: Qiu Z, et al.
Published: (2024-12-01)
by: Qiu Z, et al.
Published: (2024-12-01)
LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, <i>Limnonectes fujianensi</i>
by: Bin Li, et al.
Published: (2019-06-01)
by: Bin Li, et al.
Published: (2019-06-01)
Isolation and characterization of Boudabousia marimammalium from a mangrove habitat: identification of dual-function antimicrobial and anticancer peptides
by: Yalpi Karthik, et al.
Published: (2025-07-01)
by: Yalpi Karthik, et al.
Published: (2025-07-01)
Synergistic Antifungal Activity of Synthetic Peptides and Antifungal Drugs against <i>Candida albicans</i> and <i>C. parapsilosis</i> Biofilms
by: Leandro P. Bezerra, et al.
Published: (2022-04-01)
by: Leandro P. Bezerra, et al.
Published: (2022-04-01)
Advances in Lipid and Metal Nanoparticles for Antimicrobial Peptide Delivery
by: Marcin Makowski, et al.
Published: (2019-11-01)
by: Marcin Makowski, et al.
Published: (2019-11-01)
Novel Leech Antimicrobial Peptides, Hirunipins: Real‐Time 3D Monitoring of Antimicrobial and Antibiofilm Mechanisms Using Optical Diffraction Tomography
by: S. Dinesh Kumar, et al.
Published: (2025-03-01)
by: S. Dinesh Kumar, et al.
Published: (2025-03-01)
Anti-methicillin-resistant Staphylococcus aureus and antibiofilm activity of new peptides produced by a Brevibacillus strain
by: Abiodun Ogunsile, et al.
Published: (2023-10-01)
by: Abiodun Ogunsile, et al.
Published: (2023-10-01)
Current Status of the Application of Antimicrobial Peptides and Their Conjugated Derivatives
by: Marcel·lí del Olmo, et al.
Published: (2025-07-01)
by: Marcel·lí del Olmo, et al.
Published: (2025-07-01)
Anticancer Mechanisms and Potential Anticancer Applications of Antimicrobial Peptides and Their Nano Agents
by: Dong Z, et al.
Published: (2024-02-01)
by: Dong Z, et al.
Published: (2024-02-01)
Exploring the potential of anticancer peptides as therapeutic agents for cancer treatment
by: Reza Ghavimi, et al.
Published: (2025-03-01)
by: Reza Ghavimi, et al.
Published: (2025-03-01)
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era
by: Giacomo Rossino, et al.
Published: (2023-10-01)
by: Giacomo Rossino, et al.
Published: (2023-10-01)
Hitchhiking with Nature: Snake Venom Peptides to Fight Cancer and Superbugs
by: Clara Pérez-Peinado, et al.
Published: (2020-04-01)
by: Clara Pérez-Peinado, et al.
Published: (2020-04-01)
Exploratory data analysis of physicochemical parameters of natural antimicrobial and anticancer peptides: Unraveling the patterns and trends for the rational design of novel peptides
by: Sandeep Saini, et al.
Published: (2024-01-01)
by: Sandeep Saini, et al.
Published: (2024-01-01)
Antiviral and antibacterial peptides: Mechanisms of action
by: Mahdyeh Neghabi Hajigha, et al.
Published: (2024-11-01)
by: Mahdyeh Neghabi Hajigha, et al.
Published: (2024-11-01)
Identification and molecular cloning of novel antimicrobial peptides from skin secretions of the Chinese bamboo leaf odorous frog (Odorrana versabilis) and the North American pickerel frog (Rana palustris)
by: Yali Wu, et al.
Published: (2017-07-01)
by: Yali Wu, et al.
Published: (2017-07-01)
Designing Novel Antimicrobial Agents from the Synthetic Antimicrobial Peptide (Pep-38) to Combat Antibiotic Resistance
by: Yara Al Tall, et al.
Published: (2025-06-01)
by: Yara Al Tall, et al.
Published: (2025-06-01)
The dual interaction of antimicrobial peptides on bacteria and cancer cells; mechanism of action and therapeutic strategies of nanostructures
by: Atefeh Parchebafi, et al.
Published: (2022-06-01)
by: Atefeh Parchebafi, et al.
Published: (2022-06-01)
Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells
by: Mona Elradi, et al.
Published: (2024-03-01)
by: Mona Elradi, et al.
Published: (2024-03-01)
Peptides to Overcome the Limitations of Current Anticancer and Antimicrobial Nanotherapies
by: Valentina Del Genio, et al.
Published: (2022-06-01)
by: Valentina Del Genio, et al.
Published: (2022-06-01)
Physicochemical Features and Peculiarities of Interaction of AMP with the Membrane
by: Malak Pirtskhalava, et al.
Published: (2021-05-01)
by: Malak Pirtskhalava, et al.
Published: (2021-05-01)
The Spectrum of Design Solutions for Improving the Activity-Selectivity Product of Peptide Antibiotics against Multidrug-Resistant Bacteria and Prostate Cancer PC-3 Cells
by: Davor Juretić, et al.
Published: (2020-08-01)
by: Davor Juretić, et al.
Published: (2020-08-01)
Antimicrobial peptide temporin derivatives inhibit biofilm formation and virulence factor expression of Streptococcus mutans
by: Shangjun Jiang, et al.
Published: (2023-09-01)
by: Shangjun Jiang, et al.
Published: (2023-09-01)
Similar Items
-
Design and characterization of a new hybrid peptide from LL-37 and BMAP-27
by: Al Tall Y, et al.
Published: (2019-04-01) -
Synergistic Antibacterial Efficacy of Melittin in Combination with Oxacillin against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA)
by: Ana Flávia Marques Pereira, et al.
Published: (2023-11-01) -
Synthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
by: Arif Iftikhar Khan, et al.
Published: (2024-08-01) -
CancerGram: An Effective Classifier for Differentiating Anticancer from Antimicrobial Peptides
by: Michał Burdukiewicz, et al.
Published: (2020-10-01) -
Complementary Activities of Host Defence Peptides and Antibiotics in Combating Antimicrobial Resistant Bacteria
by: Patrick R. Lennard, et al.
Published: (2023-10-01)
