Antibiotics for preventing infection at the surgical site: Single dose vs. multiple doses

Background: Surgical site infections are common and expensive infections that can cause fatalities or poor patient outcomes. To prevent these infections, antibiotic prophylaxis is used. However, excessive antibiotic use is related to higher costs and the emergence of antimicrobial resistance. Object...

Full description

Bibliographic Details
Published in:	Saudi Pharmaceutical Journal
Main Authors:	Nehad J. Ahmed, Abdul Haseeb, PhD, Abdullmoin AlQarni, Manal AlGethamy, Ahmad J. Mahrous, Ahmed M. Alshehri, Abdullah K Alahmari, Safa S. Almarzoky Abuhussain, Ahmed Mohammed Ashraf Bashawri, Amer H. Khan
Format:	Article
Language:	English
Published:	Springer 2023-12-01
Subjects:	Antibiotics Clinical Trials Multiple Doses Single Dose Surgical Site Infections
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319016423002955

Similar Items

Dose Optimization of Colistin: A Systematic Review
by: Abdul Haseeb, et al.
Published: (2021-11-01)

A Systematic Review on Clinical Safety and Efficacy of Vancomycin Loading Dose in Critically Ill Patients
by: Abdul Haseeb, et al.
Published: (2022-03-01)

Dose optimization of vancomycin in obese patients: A systematic review
by: Mahmoud E. Elrggal, et al.
Published: (2023-03-01)

Multivariate analysis of effective dose and size-specific dose estimates for thorax and abdominal computed tomography
by: Mudasir Ashraf Shah, et al.
Published: (2023-01-01)

Unenhanced Multi-Detector Low-Dose vs Standard-Dose Computed Tomography in Patients Having Urinary Tract Calculi. A Practical Approach in Optimizing Patient's Dose, Experience at Jinnah Postgraduate Medical Center, Karachi
by: Marya Hameed, et al.
Published: (2021-09-01)

Unenhanced Multi-Detector Low-Dose vs Standard-Dose Computed Tomography in Patients Having Urinary Tract Calculi. A Practical Approach in Optimizing Patient's Dose, Experience at Jinnah Postgraduate Medical Center, Karachi
by: Marya Hameed, et al.
Published: (2021-09-01)

Radiation doses during chest examinations using dose modulation techniques in multislice CT scanner
by: Livingstone Roshan, et al.
Published: (2010-01-01)

Radiation Dose Optimization Based on Saudi National Diagnostic Reference Levels and Effective Dose Calculation for Computed Tomography Imaging: A Unicentral Cohort Study
by: Abdullah Yousef Al-Othman, et al.
Published: (2022-11-01)

Patient dose audit of the most frequent radiographic examinations and the proposed local diagnostic reference levels in southwestern Nigeria: Imperative for dose optimisation
by: N.N. Jibiri, et al.
Published: (2016-07-01)

Size-Specific Dose Estimate and Effective Dose for Pediatric Computed Tomography
by: Rukhsar Khan, et al.
Published: (2025-01-01)

High vs. Low Radiation Dose of Concurrent Chemoradiotherapy for Esophageal Carcinoma With Modern Radiotherapy Techniques: A Meta-Analysis
by: Xin Sun, et al.
Published: (2020-08-01)

Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts
by: Pamela Akuwudike, et al.
Published: (2023-12-01)

Population Pharmacokinetics and Model-Based Dose Optimization of Vancomycin in Sudanese Adult Patients with Renal Impairment
by: Ahmed KA, et al.
Published: (2024-01-01)

Erratum: Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts
by: Frontiers Production Office
Published: (2024-04-01)

The ongoing unnecessary debate regarding the risk factors for osteoradionecrosis of the jaw: Prescription dose versus mandibular doses
by: Erkan Topkan, et al.
Published: (2024-06-01)

Low-dose vs. standard-dose alteplase for acute ischemic stroke: a real-world single-center retrospective study
by: Xin-Lei Mao, et al.
Published: (2025-10-01)

Introduction of software for patient dose assessment in computed tomography
by: Nhu Tuyen Pham, et al.
Published: (2025-03-01)

Low-dose vs. standard-dose alteplase for acute ischemic stroke: a retrospective cohort study of safety and efficacy in an Iranian population
by: Fatemeh Rahimi, et al.
Published: (2025-09-01)

Modeling omics dose-response at the pathway level with DoseRider
by: Pablo Monfort-Lanzas, et al.
Published: (2025-01-01)

Stop using the flotation technique and start weighing salbutamol pressurised metered-dose inhalers without dose counters
by: Ermindo R. Di Paolo, et al.
Published: (2015-07-01)

Optimizing Radiation Dose in High-Resolution Chest CT: The Impact of Patient-Specific Factors and Size-Specific Dose Estimates
by: Mohamed Abuzaid
Published: (2025-03-01)

Contrasting Treatment- and Farm-Level Metrics of Antimicrobial Use Based on Used Daily Dose vs. Defined Daily Dose for the German Antibiotics Minimization Concept
by: Matthias Flor, et al.
Published: (2022-06-01)

Out-of-field dose in stereotactic radiotherapy for paediatric patients
by: Lachlan Garrett, et al.
Published: (2021-07-01)

Patient-specific Effective Dose Estimation from Dose–Length Product in Lung Computed Tomography Using Monte Carlo Simulation
by: Gholamreza Fallahmohammadi, et al.
Published: (2024-04-01)

Making CT Dose Monitoring Meaningful: Augmenting Dose with Imaging Quality
by: Njood Alsaihati, et al.
Published: (2023-04-01)

Monitoring Occupational Radiation Dose in Radiography Students: Implications for Safety and Training
by: Mohamed Abuzaid, et al.
Published: (2024-04-01)

A Critical Appraisal of System-Reported Organ Dose (OD) Versus Manually Calculated Mean Glandular Dose (MGD) in Dubai’s Mammography Services
by: Kaltham Abdulwahid Mohammad Noor, et al.
Published: (2025-01-01)

Impact of Number and Placement of High-dose Vertices on Equivalent Uniform Dose and Peak-to-valley Ratio for Lattice Radiotherapy
by: A. T. Bhagyalakshmi, et al.
Published: (2024-12-01)

Improving the Dosing Schedules of Targeted Anticancer Agents
by: Dominique Levêque
Published: (2025-06-01)

Three steps toward dose optimization for oncology dose finding
by: Jason J.Z. Liao, et al.
Published: (2024-08-01)

Results of eye lens doses control of medical personnel in St. Petersburg
by: Ekaterina N. Shleenkova, et al.
Published: (2020-01-01)

DOSES ASSESSMENT OF POPULATION AT LONG-TERM PERIOD AFTER THE CHERNOBYL ACCIDENT
by: N. G. Vlasova
Published: (2015-08-01)

ON THE RELATIONSHIP BETWEEN AMBIENT DOSE EQUIVALENT AND ABSORBED DOSE IN AIR IN THE CASE OF LARGE-SCALE CONTAMINATION OF THE ENVIRONMENT BY RADIOACTIVE CESIUM
by: V. P. Ramzaev, et al.
Published: (2015-10-01)

Relationship Between Effective Dose, Alternative Metrics, and SSDE: Experiences with Two CT Dose-Monitoring Systems
by: Lilla Szatmáriné Egeresi, et al.
Published: (2025-06-01)

Physician and patient preferences for dosing options in migraine prevention
by: Robert Cowan, et al.
Published: (2019-05-01)

Response Type and Host Species may be Sufficient to Predict Dose-Response Curve Shape for Adenoviral Vector Vaccines
by: John Benest, et al.
Published: (2020-03-01)

Administrative dose control for occupationally-exposed workers in Korean nuclear power plants
by: Tae Young Kong, et al.
Published: (2021-01-01)

Patients` cumulative doses during CT-examinations in Russian clinical practice
by: P. S. Druzhinina
Published: (2025-07-01)

Introducing fitting models for estimating age‐specific dose and effective dose in paediatric patients undergoing head, chest and abdomen–pelvis imaging protocols: a patient study
by: Mohammad Reza Deevband, et al.
Published: (2024-06-01)

Effect of air gap under bolus on superficial dose and depth of dose maximum during radiotherapy
by: PANG Ya, et al.
Published: (2021-10-01)