Search Results - ANTAGONIST

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    New CGRP Antagonists by H. N. Doods, M. Schindler

    Published in The Scientific World Journal (2001-01-01)
    “…The presentation will focus on BIBN 4096 BS, since this compound is still the only potent calcitonin gene-related peptide (CGRP)-antagonist described so far[1].…”
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    Article
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    Muscarinic Receptor Agonists and Antagonists by David R. Kelly, Kenneth J. Broadley

    Published in Molecules (2001-02-01)
    “…A comprehensive review of pharmacological and medical aspects of the muscarinic class of acetylcholine agonists and antagonists is presented. The therapeutic benefits of achieving receptor subtype selectivity are outlined and applications in the treatment of Alzheimer’s disease are discussed. …”
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    Differential effects of acute and chronic antagonist and an irreversible antagonist treatment on cocaine self-administration behavior in rats by Hanna N. Wetzel, Vladimir L. Tsibulsky, Andrew B. Norman

    Published in Scientific Reports (2022-05-01)
    “…Rats that self-administered cocaine were treated with the irreversible monoamine receptor antagonist, EEDQ, or were infused continuously for 14 days with the D1-like antagonist, SCH23390, treatments known to decrease or increase, respectively, the number of dopamine receptors with a concomitant decrease or increase in response to dopaminergic agonists. …”
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    Single exposure of dopamine D1 antagonist prevents and D2 antagonist attenuates methylphenidate effect by Claussen CM, Witte LJ, Dafny N

    Published in Journal of Experimental Pharmacology (2015-04-01)
    “…Single injection of D1 DA antagonist was able to significantly attenuate the locomotor activity when given prior to the initial MPD exposure and after repetitive MPD exposure, while the D2 DA antagonist partially attenuated the locomotor activity only when given before the second MPD exposure. …”
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    Antagonistic parent-offspring co-adaptation. by Mathias Kölliker, Benjamin J Ridenhour, Sabrina Gaba

    Published in PLoS ONE (2010-01-01)
    “…We show that a zone for equivalent co-adaptation outcomes exists in which stable levels of PI can evolve and be maintained despite fast strategy transitions and ongoing co-evolutionary dynamics. Under antagonistic co-adaptation, cost-free solicitation can evolve as an adaptation to emerging preferences in parents.We show that antagonistic selection across the offspring and parental life-stage of individuals favors co-adapted offspring and parental behavior within a zone of equivalent outcomes. …”
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    Secreted Wnt antagonists in scrub typhus. by Thor Ueland, Elisabeth Astrup, Kari Otterdal, Tove Lekva, Jeshina Janardhanan, John A J Prakash, Kurien Thomas, Annika E Michelsen, Pål Aukrust, George M Varghese, Jan K Damås

    Published in PLoS Neglected Tropical Diseases (2021-04-01)
    “…<h4>Conclusions/significance</h4>Our findings suggest that scrub typhus is characterized by attenuated Wnt signaling possibly involving dysregulated levels of several secreted pathway antagonists. The secreted Wnt antagonist SOST was strongly associated with renal dysfunction and poor prognosis in these patients.…”
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    ANGIOTENSIN RECEPTOR ANTAGONISTS: GOING WITH THE TIMES by E. O. Taratukhin

    “…This literature review focuses on the angiotensin II receptor antagonists as one of the new and promising classes of antihypertensive medications. …”
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    Histamine antagonists promote cancer immunosurveillance by Peng Liu, Guido Kroemer, Oliver Kepp

    Published in OncoImmunology (2023-12-01)
    “…Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.…”
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    Introduction of Leukotriene Receptor Antagonists in Manitoba by C Macie, K Wooldrage, J Manfreda, NR Anthonisen

    Published in Canadian Respiratory Journal (2006-01-01)
    “…Patient characteristics and prescribing patterns during the introduction of leukotriene receptor antagonists (LTRA) in Manitoba are described using the provincial health database. …”
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    Science as an Antagonist in Dannie Abse's poetry by Zaynab Layth Abdul Jabbar, Wafaa Abdullatif Abdulaali

    Published in Social Sciences and Humanities Open (2024-01-01)
    “…In several poems, he looks at science not only as a suspect, but as an antagonist. Such antagonism is shown, for instance, through the images he portrays for the surgeons and pathologists, whose main concerns are the medical case rather than the human condition. …”
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    TRPA1 Antagonists for Pain Relief by Ari Koivisto, Niina Jalava, Raymond Bratty, Antti Pertovaara

    Published in Pharmaceuticals (2018-11-01)
    “…Thereby, pain therapy using TRPA1 antagonists can be expected to be a superior approach when compared with many other drugs targeting single nociceptive signaling pathways. …”
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