Search Results - CENTRAL NERVOUS SYSTEM AND PHARMACOTHERAPEUTICS
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Potential interactions of central nervous system drugs used in the elderly population
Published in Brazilian Journal of Pharmaceutical Sciences (2009-06-01)Get full text
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Impact of the Renin-Angiotensin System on the Pathogeny and Pharmacotherapeutics of Neurodegenerative Diseases
Published in Biomolecules (2022-10-01)Get full text
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Multidisciplinary Pharmacotherapeutic Options for Nonalcoholic Fatty Liver Disease
Published in International Journal of Hepatology (2012-01-01)Get full text
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Japanese encephalitis in north-east, India: Pharmacotherapeutic perspectives
Published in The Microbe (2025-06-01)Get full text
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Pharmacotherapeutic profile, polypharmacy and its associated factors in a cohort of people living with HIV in Brazil
Published in AIDS Research and Therapy (2023-08-01)“…Targeted interventions should be prioritized to prevent interactions and improve treatment, especially among individuals using central nervous system and cardiovascular medications, as well as certain groups such as cisgender women, older individuals and those with lower education. …”
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Assessment of pharmacotherapeutic safety of medical prescriptions for elderly residents in a long-term care facility
Published in Brazilian Journal of Pharmaceutical Sciences (2012-09-01)“…Most of the PIM identified (53.4%) act on the central nervous system. Among the 13 different DI detected, 6 are considered PHDI. …”
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Prevalence of polypharmacy and pharmacotherapy complexity in elderly people living with HIV in Spain. POINT study
Published in Farmacia Hospitalaria (2020-07-01)“…The median number of comorbidities was 3.5 (2.0-5.0), 52.7% of them being cardiovascular; 50.0% related to the central nervous system; 17.6% hepatic; and 8.1% consisting in chronic pulmonary disease. …”
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Contribuição do uso de medicamentos para a admissão hospitalar
Published in Brazilian Journal of Pharmaceutical Sciences (2009-03-01)Get full text
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Review of Intranasal Active Pharmaceutical Ingredient Delivery Systems
Published in Pharmaceuticals (2024-09-01)“…In recent decades, there has been an increased interest in the development of intranasal delivery systems for active pharmaceutical ingredients (APIs) not only for treating local nasal diseases but also for treating systemic diseases, central nervous system (CNS) disorders, and vaccine delivery. …”
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Proteomic and metabolomic signatures of U87 glioblastoma cells treated with cisplatin and/or paclitaxel
Published in Annals of Medicine (2023-12-01)Get full text
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Bridging regional neurovascular unit heterogeneity and cognitive function: a review
Published in Fluids and Barriers of the CNS (2025-08-01)Get full text
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The new European Medicines Agency guideline on antidepressants: a guide for researchers and drug developers
Published in European Psychiatry (2024-01-01)Get full text
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Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations
Published in Antibiotics (2023-03-01)Get full text
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Hippocampal Ganglioside Composition is Altered by Metformin and Liraglutide Treatment in A High-Fat High-Sugar Diet Rat Model
Published in Acta Clinica Croatica (2023-01-01)“…Insulin resistance has many deleterious effects on the central nervous system, including the initiation and potentiation of neurodegeneration. …”
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Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats
Published in Frontiers in Aging Neuroscience (2020-01-01)“…Fortunately, intranasal administration of native orexin peptides circumvents this issue and others concerning peptide transport into the central nervous system (CNS). To investigate the ability of intranasal orexin-A (OxA) administration to improve the anatomical, neurochemical, and behavioral substrates of age-related cognitive dysfunction, these studies utilized a rodent model of aging combined with acute intranasal administration of saline or OxA. …”
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Investigation of key interactions between the second extracellular loop of dopamine D2 receptor and several hydroxy-N-{[2-(4-phenyl-piperaziny-1-yl)ethyl]phenyl}-nicotinamides
Published in Journal of the Serbian Chemical Society (2014-01-01)“…Dopaminergic receptor system has been in focus for the development of new pharmacotherapeutic agents, targeting number of central nervous system related disorders, like drug addiction, schizophrenia, depression, and Parkinson's disease, just to name a few. …”
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The involvement of K+ channels in depression and pharmacological effects of antidepressants on these channels
Published in Translational Psychiatry (2024-10-01)“…It is well documented that K+ channels serve crucial roles in modulating the neuronal excitability and neurotransmitter release in the brain, and abnormality of these channels participated in the pathogenic process of diverse central nervous system (CNS) pathologies, such as seizure and Alzheimer’s disease (AD). …”
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